Tumor cell intravasation [PDF]
American Journal of Physiology-Cell Physiology, 2016 The process of entering the bloodstream, intravasation, is a necessary step in the development of distant metastases. The focus of this review is on the pathways and molecules that have been identified as being important based on current in vitro and in vivo assays for intravasation.
Serena P H, Chiang +2 more
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Scientific Reports, 2021 Liquid biopsy is a tool to unveil resistance mechanisms in NSCLC. We studied changes in gene expression in CTC-enriched fractions of EGFR-mutant NSCLC patients under osimertinib.
Aliki Ntzifa +5 more
doaj +1 more source
Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook
Molecular Oncology, 2021 Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐time follow‐up of cancer and overcomes many limitations of tissue biopsies.
Evi Lianidou
doaj +1 more source
Tumor-reactive immune cells protect against metastatic tumor and induce immunoediting of indolent but not quiescent tumor cells [PDF]
, 2016 Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppressor cells and poor immunogenicity of the tumor-expressing self-antigens.
Bear, Harry D. +8 more
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CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs)
Cells, 2019 Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process.
Tala Tayoun +5 more
doaj +1 more source
Extracellular Matrix Protein Tenascin C Increases Phagocytosis Mediated by CD47 Loss of Function in Glioblastoma. [PDF]
, 2019 Glioblastomas (GBM) are highly infiltrated by myeloid-derived innate immune cells that contribute to the immunosuppressive nature of the brain tumor microenvironment (TME).
Gao, Peisong +14 more
core +2 more sources
Frontiers in Cell and Developmental Biology, 2021 Purpose: Monocarboxylate transporter 4 (MCT4) can influence the amount of lactate in the tumor microenvironment and further control cancer cell proliferation, migration, and angiogenesis.
Athina Markou +6 more
doaj +1 more source
Base composition of DNA in adenovirus-12-induced tumor [PDF]
, 1969 A series of experiments was conducted to study the base composition of DNA in AVl2-induced tumor and host cells by paper chromatography, and it was found that DNA per cent. guanine-cystosine contents were around 42 % in both of them. The base composition
Ohmori, Masaki
core +1 more source
Interactions of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL) with the Immune System: Implications for Inflammation and Cancer [PDF]
, 2019 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily. TRAIL has historically been distinct from the Fas ligand and TNFα in terms of selective apoptosis induction in tumor cells and has a nearly non ...
Baukloh, Ann-Kathrin +5 more
core +1 more source
Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells [PDF]
, 2018 Tumor cells release extracellular microvesicles (MVs) in the microenvironment to deliver biological signals to neighbouring cells as well as to cells in distant tissues.
Battisti, Federico +11 more
core +1 more source