Results 21 to 30 of about 14,776,627 (313)
Molecular Oncology, 2021 MLL3 histone methyltransferase, encoded by the KMT2C gene, is a tumor suppressor that has an essential role in cell‐type‐specific gene expression.
Sofia Mastoraki +5 more
doaj +1 more source
TIMER2.0 for analysis of tumor-infiltrating immune cells
Nucleic Acids Res., 2020 Tumor progression and the efficacy of immunotherapy are strongly influenced by the composition and abundance of immune cells in the tumor microenvironment.
Taiwen Li +7 more
semanticscholar +1 more source
Analysis of the mechanisms regulating soluble PD-1 production and function in human NK cells
Frontiers in Immunology, 2023 NK cells represent important effectors that play a major role in innate defences against pathogens and display potent cytolytic activity against tumor cells. An array of surface receptors finely regulate their function and inhibitory checkpoints, such as
Francesca Romana Mariotti +6 more
doaj +1 more source
Frontiers in Physiology, 2020 Signaling pathways involve complex molecular interactions and are controled by non-linear regulatory mechanisms. If details of regulatory mechanisms are not fully elucidated, they can be implemented by different, equally reasonable mathematical ...
Janina Mothes +5 more
doaj +1 more source
Circulating tumor cells in genitourinary tumors [PDF]
Therapeutic Advances in Urology, 2017 Management of advanced urogenital malignancies has profoundly changed in recent years due to the development of novel targeted drugs that have significantly improved patient’s clinical outcomes. This process has been made possible mainly thanks to better knowledge of tumor genetic alterations and molecular altered pathways.
Massari, Francesco +8 more
openaire +4 more sources
Scientific Reports, 2021 Liquid biopsy is a tool to unveil resistance mechanisms in NSCLC. We studied changes in gene expression in CTC-enriched fractions of EGFR-mutant NSCLC patients under osimertinib.
Aliki Ntzifa +5 more
doaj +1 more source
Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook
Molecular Oncology, 2021 Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐time follow‐up of cancer and overcomes many limitations of tissue biopsies.
Evi Lianidou
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Purpose: Monocarboxylate transporter 4 (MCT4) can influence the amount of lactate in the tumor microenvironment and further control cancer cell proliferation, migration, and angiogenesis.
Athina Markou +6 more
doaj +1 more source
TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells.
Cancer Research, 2017 Recent clinical successes of cancer immunotherapy necessitate the investigation of the interaction between malignant cells and the host immune system. However, elucidation of complex tumor-immune interactions presents major computational and experimental
Taiwen Li +7 more
semanticscholar +1 more source
CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs)
Cells, 2019 Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process.
Tala Tayoun +5 more
doaj +1 more source