Results 41 to 50 of about 14,776,627 (313)
Glucose transporters in cancer – from tumor cells to the tumor microenvironment
The FEBS Journal, 2018 Solute carriers of the glucose transporter (GLUT) family mediate the first step for cellular glucose usage. The upregulation of GLUTs has been reported in numerous cancer types as a result of perturbation of gene expression or protein relocalization or ...
P. Ancey, Caroline Contat, E. Meylan
semanticscholar +1 more source
Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy.
Cancer Discovery, 2016 UNLABELLED "Liquid biopsy" focusing on the analysis of circulating tumor cells (CTC) and circulating cell-free tumor DNA (ctDNA) in the blood of patients with cancer has received enormous attention because of its obvious clinical implications for ...
C. Alix-Panabières, K. Pantel
semanticscholar +1 more source
, 2020 What Are CTCs? One of the major challenges in treating cancer is getting “all” of the cancer, including the parts we cannot see. Even if surgery, chemotherapy, or radiation removes all traces of known cancer, there is still a risk of the cancer returning,
Michael Alvarado
semanticscholar +1 more source
Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy [PDF]
, 2017 Adhesion to extracellular matrix (ECM) is crucially important for survival of normal epithelial cells as detachment from ECM triggers specific apoptosis known as anoikis.
A C Belkina +7 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2022 Non-canonical secretion pathways, collectively known as unconventional protein secretion (UPS), are alternative secretory mechanisms usually associated with stress-inducing conditions.
Rebeca Piatniczka Iglesia +18 more
doaj +1 more source
Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]
, 2018 Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz +431 more
core +2 more sources
Rigorous results of limiting behaviors of total tumor size under cyclic intermittent therapy for the system of reversible phenotype-switchable tumor cells [PDF]
arXiv, 2023 We are keenly interested in finding the limiting behaviors of total tumor size when tumor cells are subject to the periodic repetition of therapy and rest periods, called intermittent cyclic therapy. We hypothesize that each tumor cell can take either therapy-sensitive or therapy-tolerant phenotype, its phenotype transition is mainly driven by the ...
arxiv
Journal of Experimental Medicine, 2017 It is unclear whether PD-L1 on tumor cells is sufficient for tumor immune evasion or simply correlates with an inflamed tumor microenvironment. We used three mouse tumor models sensitive to PD-1 blockade to evaluate the significance of PD-L1 on tumor ...
Vikram R. Juneja +7 more
semanticscholar +1 more source
Effect of immunization with fetal cells on adenovirus-12 oncogenesis [PDF]
, 1974 The effect of immunization with hamster fetal cells on the tumor induction by adnovirus type 12 was studied by in vivo and in vitro. The immunization with lO-day old fetal cells showed a recognizable inhibition on the tumor induction by adenovirus type ...
Abe, Shinji
core +1 more source
Essential gene pathways for glioblastoma stem cells: clinical implications for prevention of tumor recurrence. [PDF]
, 2011 Glioblastoma (World Health Organization/WHO grade IV) is the most common and most aggressive adult glial tumor. Patients with glioblastoma, despite being treated with gross total resection and post-operative radiation/chemotherapy, will almost always ...
Choe, Jinny +6 more
core +1 more source