Results 51 to 60 of about 14,776,627 (313)

The PPARγ Agonist Rosiglitazone Suppresses Syngeneic Mouse SCC (Squamous Cell Carcinoma) Tumor Growth through an Immune-Mediated Mechanism [PDF]

, 2019
Recent evidence suggests that PPARγ agonists may promote anti-tumor immunity. We show that immunogenic PDV cutaneous squamous cell carcinoma (CSCC) tumors are rejected when injected intradermally at a low cell number (1 × 106) into immune competent ...
Derr-Yellin, Ethel, Ermatov, Nurmukambed, Konger, Raymond L., Ren, Lu, Sahu, Ravi P.   +4 more
core   +1 more source

A Metabolic Reprogramming Amino Acid Polymer as an Immunosurveillance Activator and Leukemia Targeting Drug Carrier for T‐Cell Acute Lymphoblastic Leukemia

Advanced Science, 2022
Compromised immunosurveillance leads to chemotherapy resistance and disease relapse of hematological malignancies. Amino acid metabolism regulates immune responses and cancer; however, a druggable amino acid metabolite to enhance antitumor ...
Changzheng Li, Xinru You, Xi Xu, Binghuo Wu, Yuye Liu, Tong Tong, Jie Chen, Yishan Li, Chunlei Dai, Zhitao Ye, Xiaobin Tian, Yan Wei, Zechen Hao, Linjia Jiang, Jun Wu, Meng Zhao   +15 more
doaj   +1 more source

Effect of astragaloside Ⅳ on SK ⁃ N ⁃ SH cells damage induced by 1 ⁃ methyl ⁃ 4 ⁃ phenylpyridine in Parkinson's disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2022
Objective To investigate the effect of astragaloside Ⅳ on the injury of SK⁃N⁃SH cell in Parkinson's disease (PD) induced by 1 ⁃ methy ⁃ 4 ⁃ phenylpyridine (MPP＋) and its mechanism.
HUANG Xiao⁃jing, HUANG Huai, XU Zheng⁃hu, HUANG Wan⁃gang, YANG Dong⁃feng, REN He⁃cheng   +5 more
doaj   +1 more source

Interactions of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL) with the Immune System: Implications for Inflammation and Cancer [PDF]

, 2019
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily. TRAIL has historically been distinct from the Fas ligand and TNFα in terms of selective apoptosis induction in tumor cells and has a nearly non ...
Baukloh, Ann-Kathrin, Beyer, Katharina, Kamphues, Carsten, Kotsch, Katja, Sattler, Arne, Stoyanova, Ani   +5 more
core   +1 more source

The predictive value of total-body PET/CT in non-small cell lung cancer for the PD-L1 high expression

Frontiers in Oncology, 2022
PurposeTotal-body positron emission tomography/computed tomography (PET/CT) provides faster scanning speed, higher image quality, and lower injected dose.
Bingxin Hu, Huibin Jin, Xiali Li, Xinyu Wu, Junling Xu, Yongju Gao   +5 more
doaj   +1 more source

Tumor Cells Circulate in the Peripheral Blood of All Major Carcinomas but not in Healthy Subjects or Patients With Nonmalignant Diseases

Clinical Cancer Research, 2004
Purpose: The purpose of this study was to determine the accuracy, precision, and linearity of the CellSearch system and evaluate the number of circulating tumor cells (CTCs) per 7.5 mL of blood in healthy subjects, patients with nonmalignant diseases ...
W. Allard, J. Matera, M. Miller, M. Repollet, M. Connelly, C. Rao, A. Tibbe, J. Uhr, L. Terstappen   +8 more
semanticscholar   +1 more source

The rationale for liquid biopsy in colorectal cancer: focus on circulating tumor cells [PDF]

, 2015
Capturing circulating tumor cells (CTCs) and/or circulating tumor DNA from blood, which represents a precious source of biological material derived from both primary and metastatic tumors, has been named a 'liquid biopsy'. While the circulating tumor DNA
Carletti, Raffaella, Cortesi, Enrico, DI GIOIA, Cira Rosaria Tiziana, Gazzaniga, Paola, Gradilone, Angela, Nicolazzo, Chiara, Raimondi, Cristina   +6 more
core   +1 more source

Therapeutic potential of NR4A1 in cancer: Focus on metabolism

Frontiers in Oncology, 2022
Metabolic reprogramming is a vital hallmark of cancer, and it provides the necessary energy and biological materials to support the continuous proliferation and survival of tumor cells. NR4A1 is belonging to nuclear subfamily 4 (NR4A) receptors.
Shan Deng, Bo Chen, Jiege Huo, Xin Liu, Xin Liu   +4 more
doaj   +1 more source

TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells.

Cancer Research, 2018
Neutrophils play a critical role in cancer, with both protumor and antitumor neutrophil subpopulations reported. The antitumor neutrophil subpopulation has the capacity to kill tumor cells and limit metastatic spread, yet not all tumor cells are equally ...
Maya Gershkovitz, Yaki Caspi, Tanya Fainsod-Levi, Ben Katz, Janna Michaeli, Saleh Khawaled, S. Lev, L. Polyansky, M. Shaul, Ronit Vogt Sionov, L. Cohen-Daniel, R. Aqeilan, Y. Shaul, Y. Mori, R. Karni, Z. Fridlender, A. Binshtok, Z. Granot   +17 more
semanticscholar   +1 more source

Enhancement of experimental metastasis by tumor necrosis factor [PDF]

, 1993
The influence of endogenous and exogenous tumor necrosis factor (TNF) on metastasis was investigated in an experimental fibrosarcoma metastasis model.
Echtenacher, Bernd, Falk, Werner, Männel, Daniela N., Orosz, P., Rüschoff, J., Weber, D.   +5 more
core   +2 more sources