Results 71 to 80 of about 14,776,627 (313)

Recombinant Listeria promotes tumor rejection by CD8+ T cell-dependent remodeling of the tumor microenvironment. [PDF]

, 2018
Agents that remodel the tumor microenvironment (TME), prime functional tumor-specific T cells, and block inhibitory signaling pathways are essential components of effective immunotherapy.
Barajas, Gonzalo, Deng, Weiwen, Desbien, Anthony L, Dubensky, Thomas W, Flores, Ruben, Hanson, William G, Hudson, Thomas E, Katibah, George E, Lauer, Peter, Lemmens, Edward E, Leong, Meredith L, Lira, Victor, Portnoy, Daniel A   +12 more
core   +1 more source

Down-regulation of the Lamin A/C in neuroblastoma triggers the expansion of tumor initiating cells [PDF]

, 2015
Tumor-initiating cells constitute a population within a tumor mass that shares properties with normal stem cells and is considered responsible for therapy failure in many cancers.
AMENDOLA, Donatella, Bearzi, Claudia, Bucci, Barbara, Camerlingo, Rosalba, CARICO, ELISABETTA, D'Agnano, Igea, DOMINICI, Carlo, Felsani, Armando, Guglielmi, Loredana, Iannetti, Ilaria, Leonetti, Carlo, MARESCA, GIOVANNA, MEGIORNI, Francesca, Mercanti, Delio, MILAN, MARIKA, Musa, Carla, Nardella, Marta, Pirozzi, Giuseppe, Porru, Manuela, Rizzi, Roberto, Sessa, Giuseppe   +20 more
core   +2 more sources

PIK3CA hotspot mutations in circulating tumor cells and paired circulating tumor DNA in breast cancer: a direct comparison study

Molecular Oncology, 2019
Liquid biopsy analysis, mainly based on circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA), provides an extremely powerful tool for the molecular profiling of cancer patients in real time.
Eleni Tzanikou, Athina Markou, Eleni Politaki, Anastasios Koutsopoulos, Amanda Psyrri, Dimitris Mavroudis, Vassilis Georgoulias, Evi Lianidou   +7 more
doaj   +1 more source

Tumor Growth with Nutrients: Regularity and Stability [PDF]

arXiv, 2022
In this paper we study a tumor growth model with nutrients. The model presents dynamic patch solutions due to the contact inhibition among the tumor cells. We show that when the nutrients do not diffuse and the cells do not die, the tumor density exhibits regularizing dynamics.
arxiv  

Ethical Implications in the Use of Embryonic and Adult Neural Stem Cells

Stem Cells International, 2012
The advent and growth of technological advances have led to new routes of knowledge. Thereby, we currently face new challenges. We have just started to get a glimpse of the structural and functional role of neural stem cells in differentiation and ...
Rodrigo Ramos-Zúñiga, Oscar González-Pérez, Ana Macías-Ornelas, Vivian Capilla-González, Alfredo Quiñones-Hinojosa   +4 more
doaj   +1 more source

Current detection technologies for circulating tumor cells.

Chemical Society Reviews, 2017
Circulating tumor cells (CTCs) are cancer cells that circulate in the blood stream after being naturally shed from original or metastatic tumors, and can lead to a new fatal metastasis.
Zheyu Shen, A. Wu, Xiaoyuan Chen
semanticscholar   +1 more source

Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells [PDF]

, 2018
Tumor cells release extracellular microvesicles (MVs) in the microenvironment to deliver biological signals to neighbouring cells as well as to cells in distant tissues.
Battisti, Federico, Belleudi, Francesca, Claudia De Archangelis,, DI FILIPPO, Alessandra, Dionisi, Marco, Napoletano, Chiara, Nuti, Marianna, RAHIMI KOSHKAKI, Hassan, Rughetti, Aurelia, Ruscito, Ilary, Torrisi, Maria Rosaria, Zizzari, ILARIA GRAZIA   +11 more
core   +1 more source

Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration

eLife, 2020
The sox2 expressing (sox2+) progenitors in adult mammalian inner ear lose the capacity to regenerate while progenitors in the zebrafish lateral line are able to proliferate and regenerate damaged HCs throughout lifetime. To mimic the HC damage in mammals,
Zhian Ye, Zhongwu Su, Siyu Xie, Yuye Liu, Yongqiang Wang, Xi Xu, Yiqing Zheng, Meng Zhao, Linjia Jiang   +8 more
doaj   +1 more source

Overcoming the Heat Endurance of Tumor Cells by Interfering with the Anaerobic Glycolysis Metabolism for Improved Photothermal Therapy.

ACS Nano, 2017
In this study, we developed a general method to decorate plasmonic gold nanorods (GNRs) with a CD44-targeting functional polymer, containing a hyaluronic acid (HA)-targeting moiety and a small molecule Glut1 inhibitor of diclofenac (DC), to obtain GNR/HA-
Wei‐Hai Chen, G. Luo, Qi Lei, Sheng Hong, Wen-Xiu Qiu, Li‐Han Liu, Si-Xue Cheng, Xianzheng Zhang   +7 more
semanticscholar   +1 more source

Immunobiology of solid cancers: cellular and molecular pathways as potential diagnostic and therapeutic targets [PDF]

, 2018
In the last four decades, tumor immunology has shed light on identity and functions of cells and molecules involved in tumor rejection through the involvement of the immune system [1].
Braicu, E. I., Gasparri, M. L., Ruscito, I., Zizzari, I. G.   +3 more
core   +3 more sources