Results 81 to 90 of about 14,776,627 (313)
Regulation of Tumor Immunity by Tumor/Dendritic Cell Fusions [PDF]
, 2010 The goal of cancer vaccines is to induce antitumor immunity that ultimately will reduce tumor burden in tumor environment. Several strategies involving dendritic cells- (DCs)- based vaccine incorporating different tumor-associated antigens to induce ...
Gong, Jianlin +10 more
core +4 more sources
Pathology & Oncology Research, 2004 Stem cells possess two basic characteristics: they are able to renew themselves and to develop into different cell types. The link between normal stem cells and tumor cells could be examined in three aspects: what are the differences and similarities in the control of self-renewal capacity between stem cells and tumor cells; whether tumor cells arise ...
Melinda Hajdú, László Kopper
openaire +3 more sources
Global Stability of a PDE-ODE model for acid-mediated tumor invasion [PDF]
arXiv, 2023 In this paper, we study the global dynamics of a general reaction-diffusion model based on acid-mediated invasion hypothesis, which is a candidate explanation for the Warburg effect. A key feature of this model is the density-limited tumor diffusion term for tumor cells, which might give rise to the degeneracy of the parabolic equation. Our theoretical
arxiv
Circulating and disseminated tumor cells: harbingers or initiators of metastasis?
Molecular Oncology, 2017 Tumor cells leave the primary tumor and enter the circulation. Once there, they are called circulating tumor cells (CTCs). A fraction of CTCs are capable of entering distant sites and persisting as disseminated tumor cells (DTCs).
A. Dasgupta +2 more
semanticscholar +1 more source
Trypsin digest of cancer cells surface stimulates anti-tumor immune response better than cancer cells themselves [PDF]
, 2010 Antigens expressed on the surface of cancer cells are accessible targets for both humoral and cell-mediated immune responses, and are therefore potential candidates for vaccine development.
Balashova Elena, Petr Lokhov
core +2 more sources
TLR2/4 are novel activating receptors for SARS-CoV-2 spike protein on NK cells
Frontiers in ImmunologyBackgroundIn early infected or severe coronavirus disease 2019 (COVID-19) patients, circulating NK cells are consistently reduced, despite being highly activated or exhausted.
Nadine Landolina +13 more
doaj +1 more source
Cells, 2019 Expression of the androgen receptor splice variant 7 (ARV7) in circulating tumor cells (CTCs) has been associated with resistance towards novel androgen receptor (AR)-targeting therapies. While a multitude of ARV7 detection approaches have been developed,
Claudia Hille +9 more
doaj +1 more source
Probabilistic approach to a proliferation and migration dichotomy in the tumor cell invasion [PDF]
, 2007 The proliferation and migration dichotomy of the tumor cell invasion is examined within a two-component continuous time random walk (CTRW) model. The balance equations for the cancer cells of two phenotypes with random switching between cell proliferation and migration are derived. The transport of tumor cells is formulated in terms of the CTRW with an
arxiv +1 more source
Experimental oncology, 2014 The paper deals with the analysis of literary data on the tumor cell heterogeneity. Phenotypic, genetic and epigenetic mechanisms of heterogeneity are considered. The heterogeneity of metastasis is considered too. The importance for the biology of populations of tumor cells and the sensitivity of tumors to therapeutic treatment are discussed.
Chekhun, V.F. +2 more
openaire +3 more sources
T cells in the microenvironment of solid pediatric tumors: the case of neuroblastoma
Frontiers in ImmunologyNeuroblastoma (NB) is an immunologically “cold” tumor with poor or no inflamed substrates as most of solid pediatric tumors (SPT). Consistent data indicate that NB tumor microenvironment (TME) is dominated by myeloid cells, with little (but variable) T ...
Enrico Maggi +7 more
doaj +1 more source