Results 21 to 30 of about 6,600 (156)

Efeito do miriadenolídeo isolado de Alomia myriadenia (Asteraceae) sobre o tumor de Erlich ascítico no camundongo Effect of myriadenolide isolated from Alomia myriadenia (Asteraceae) on Ehrlich tumor in its ascitic form

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2006
Estudou-se atividade antineoplásica de um produto natural isolado de Alomia myriadenia (miriadenolídeo) no modelo do tumor de Ehrlich em camundongos. Dezoito fêmeas de camundongo Swiss foram inoculadas com 2x10(7) células viáveis de tumor de Ehrlich via ...
D. Verçosa Júnior, E.M. Souza-Fagundes, G.D. Cassali, E.L. Ribeiro, C.L. Zani, M.M. Melo   +5 more
doaj   +1 more source

Efeito do hipotireoidismo no tumor de Ehrlich sólido em camundongos fêmeas castradas e não castradas [PDF]

Arquivos Brasileiros de Endocrinologia & Metabologia, 2004
Foi estudado o efeito do hipotireoidismo, induzido pelo propiltiouracil (PTU), no tumor de Ehrlich sólido, implantado em camundongos fêmeas adultas castradas ou não. Foram utilizados 40 animais distribuídos em quatro grupos: hipotireóideo castrado, hipotireóideo não castrado, eutireóideo castrado e eutireóideo não castrado.
Silva, Alessandra Estrêla da, Serakides, Rogéria, Ferreira, Enio, Moraes, Jáder R. Cappi, Ocarino, Natália de Melo, Cassali, Geovanni Dantas   +5 more
openaire   +3 more sources

In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

EMBO Molecular Medicine, 2018
Chimeric antigen receptor (CAR) T cells brought substantial benefit to patients with B‐cell malignancies. Notwithstanding, CAR T‐cell manufacturing requires complex procedures impeding the broad supply chain. Here, we provide evidence that human CD19‐CAR
Anett Pfeiffer, Frederic B Thalheimer, Sylvia Hartmann, Annika M Frank, Ruben R Bender, Simon Danisch, Caroline Costa, Winfried S Wels, Ute Modlich, Renata Stripecke, Els Verhoeyen, Christian J Buchholz   +11 more
doaj   +1 more source

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

Advanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng, Peng Yue, Kaiyu Zhou, Guidong Gong, Yue Zhang, Sha Lin, Xu Liu, Yanjiang Zheng, Siyuan Jing, Junling Guo, Yan Qi, Bi‐Sen Ding, Yimin Hua, Yifei Li   +13 more
wiley   +1 more source

Der Chromosomenbestand des Ehrlich-Ascites-Tumors der Maus

Zeitschrift für Naturforschung B, 1952
Es werden der durch erhöhte Zahl und besonders geformte Elemente vom normalen abweichende Chromosomenbestand der Asciteszellen und seine Variationen beschrieben.
openaire   +1 more source

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

Efeito do tratamento com própolis de Scaptotrigona aff. postica sobre o desenvolvimento do tumor de Ehrlich em camundongos [PDF]

Revista Brasileira de Farmacognosia, 2010
Neste trabalho foi investigado o efeito do extrato hidroalcoolico de propolis (EHP) de Scaptotrigona aff. postica sobre o desenvolvimento do tumor de Ehrlich na forma solida, sobre a celularidade dos orgaos linfoides dos animais portadores de tumor, bem como, sobre a producao de oxido nitrico (NO) pelos macrofagos destes animais.
Araújo, Maria José A. M., Dutra, Richard P., Costa, Graciomar C., Reis, Aramys S., Assunção, Anne K. M., Libério, Silvana A., Maciel, Márcia C. G., Silva, Lucilene A., Guerra, Rosane N. M., Ribeiro, Maria N. S., Nascimento, Flávia R. F.   +10 more
openaire   +3 more sources

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Estudos preliminares da imunidade celular no tumor de Ehrlich

Revista da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo, 1988
The animal immune system may be regarded as composed of lymphocytes, macrophages, a series of related cells and their soluble products found in different tissues and organs. In the Ehrlich tumour, the phenomenon of antibody dependent cellular cytotoxicity was shown to be efficient.
openaire   +2 more sources

Real‐world progression‐free survival and overall survival in patients with HR+/HER2− advanced breast cancer treated in first‐line with ribociclib, endocrine monotherapy or chemotherapy: Results from the observational RIBANNA study

International Journal of Cancer, EarlyView.
What's New? The CDK4/6 inhibitor ribociclib in combination with an endocrine‐based therapy has demonstrated significant progression‐free and overall survival benefits in patients with advanced/metastatic HR+/HER2‐ breast cancer in the pivotal MONALEESA trials.
Peter A. Fasching, Cosima Brucker, Thomas Decker, Anne Engel, Thomas Göhler, Christian Jackisch, Jan Janssen, Andreas Köhler, Kerstin Lüdtke‐Heckenkamp, Diana Lüftner, Frederik Marmé, Marion van Mackelenbergh, Beate Rautenberg, Marcus Schmidt, Rudolf Weide, Pauline Wimberger, Elena Kisseleff, Christina Pfister, Claudia Quiering, Christian Roos, Achim Wöckel   +20 more
wiley   +1 more source