Results 31 to 40 of about 63,140,021 (193)

Advanced In Vitro Platforms for Experimental Liver Research: From Organoids and Liver‐on‐Chip to Omics and Artificial Intelligence

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hepatocytes perform essential physiological functions in the human body. Gaining more profound insight into the liver structure, diseases, and physiology by using in vitro models can help to propose more relevant clinical applications. Conventional in vitro liver models, such as two‐dimensional (2D) cell cultures, fail to adequately replicate ...
Seyedeh Kiana Teymorian, Pedram Asadi Sarabi, Abbas Piryaei, Massoud Vosough   +3 more
wiley   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

Synthesis, Cytotoxicity, and Apoptosis‐Associated Cell Death Activity of an Isatin‐Containing Pyrimidine‐Derived Cu(II) Complex

Journal of Applied Toxicology, EarlyView.
ABSTRACT A Cu(II) complex derived from a pyrimidine with the isatin group was synthesized and tested for its cytotoxic effects on A549 lung cancer and MCF‐7 breast cancer cell lines, as well as its effects on apoptosis‐associated cell death and cell cycle regulation in A549 cells. To evaluate cytotoxicity, MTT assays were performed at 24, 48, and 72 h,
Müjgan Kesik Oktay, Cansu Topkaya, Elif Kağa, Yasin Eren, Ramazan Güp   +4 more
wiley   +1 more source

Parameters of the models for the Ehrlich tumor.

, 2019
Parameters of the models for the Ehrlich tumor.
Antonio Rafael Selva Castañeda (7854617), Victoriano Gustavo Sierra González (7854632), Erick Ramírez Torres (7854620), Maraelys Morales González (7854626), Luis Enrique Bergues Cabrales (7854641), Juan Ignacio Montijano (7854638), Narciso Antonio Villar Goris (7854623), María Schonbek (7854635), Juan Bory Reyes (7854629)   +8 more
core   +1 more source

The Crude Venom of the Whitetail Lancehead, Bothrops leucurus, and Two of Its Enzymatic Components Are Selectively Cytotoxic for Glioma Cells In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Malignant glioma is the most common primary brain tumor, and glioblastoma multiforme (GBM) remains its most aggressive and incurable form. Snake venoms contain bioactive compounds with promising antitumoral properties against several cancer types.
M. O. H. V. Rosário, T. M. Fucase, P. J. Spencer, J. M. Sciani, J. Clarêncio, G. Rádis‐Baptista, L. L. Casais‐e‐Silva, R. S. El‐Bachá   +7 more
wiley   +1 more source

The anticancer activity of dichloromethane crude extract obtained from Calea pinnatifida

Journal of Experimental Pharmacology, 2012
Gabriela M Marchetti,1,2 Karina A Silva,3 Arianny N Santos,3 Ilza MO Sousa,3 Sirlene V Tinti,2 Glyn M Figueira,4 Mary A Foglio,1,3 João E Carvalho1,21Programa de Pós Graduação em Biologia Celular e Estrutural ...
Foglio MA, Figueira GM, Tinti SV, Sousa IM, Santos AN, Silva KA, Marchetti GM, Carvalho JE   +7 more
doaj  

Graphene Oxide Theranostic Effect: Conjugation of Photothermal and Photodynamic Therapies Based on an in vivo Demonstration

International Journal of Nanomedicine, 2021
Maria P Romero,1,2 Hilde H Buzza,1 Mirian D Stringasci,1 Bianca M Estevão,1 Cecilia CC Silva,3 Marcelo A Pereira-da-Silva,1 Natalia M Inada,1 Vanderlei S Bagnato1 1São Carlos Institute of Physics, IFSC/USP, São Carlos, São ...
Romero MP, Buzza HH, Stringasci MD, Estevão BM, Silva CCC, Pereira-da-Silva MA, Inada NM, Bagnato VS   +7 more
doaj  

VIII Congresso Mundial de Cirurgia Oncológica; VIII Congresso Brasileiro de Cirurgia Oncológica; V GASTRINCA; I Simpósio de Enfermagem em Cirurgia Oncológica

Revista Brasileira de Cancerologia, 2010
Resumos escolhidos para publicação. Nessa edição, os títulos foram: Traquelectomia Radical Abdominal para Tratamento do Câncer do Colo do Útero Invasor: Relato de Caso; Hemipelvectomia: Experiência do Hospital Erasto Gaertner com 32 Casos em Dez Anos ...
Instituto Nacional de Câncer José de Alencar Gomes da Silva
doaj   +1 more source

Balancing coherence and resonance through linguistic framing: A longitudinal study of German biotechnology ventures' responses to the Covid‐19 pandemic

Strategic Entrepreneurship Journal, EarlyView.
Abstract Research Summary Research suggests that ventures benefit from framing to gain audience support, yet how they utilize framing when exogenous shocks redirect attention remains unclear. Drawing on a longitudinal multiple‐case study of six biotechnology ventures following the COVID‐19 pandemic, we show how ventures balance coherence and resonance ...
Niklas Dreymann, Indre Maurer
wiley   +1 more source