Results 51 to 60 of about 6,600 (156)

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

An Overview of Liquid Chromatography–Mass Spectrometry (LC–MS) Methods for the Quantification of Antibody‐Drug Conjugates

Biomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT Antibody‐drug conjugates (ADCs) are innovative drugs composed of cytotoxic molecules (payload) linked to antibodies, that selectively target and kill cancer cells upon internalization. In vivo, ADCs exist as intact molecules, naked antibodies, or released, unconjugated (linker‐)payload.
Pauline L. M. Buitelaar, Hilde Rosing, Jos H. Beijnen, Neeltje Steeghs, Alwin D. R. Huitema   +4 more
wiley   +1 more source

Ricinus Communis: Nutritional Importance, Health Benefits, and Industrial Applications

eFood, Volume 7, Issue 1, February 2026.
The current paper summarizes the nutritional composition, phytochemistry, health benefits, safety studies, and applications of castor beans and their oil. Moreover, the diverse bioactive compounds, including saponins, emodins, terpenoids, anthraquinones, flavonoids, steroids, and alkaloids, exhibit therapeutic properties such as antioxidant, anticancer,
Hassan Raza, Muhammad Tauseef Sultan, Asad Abbas, Aimen Mazhar, Ahmad Mujtaba Noman, Muhammad Imran, Muzzamal Hussain, Ehab M. Mostafa, Ahmed H. El‐Ghorab, Mohammed M. Ghoneim, Samy Selim, Mohamed A. Abdelgawad, Anjuman Gul Memon, Entessar Al Jbawi   +13 more
wiley   +1 more source

AML-VAC-XS15-01: protocol of a first-in-human clinical trial to evaluate the safety, tolerability and preliminary efficacy of a multi-peptide vaccine based on leukemia stem cell antigens in acute myeloid leukemia patients

Frontiers in Oncology
IntroductionAcute myeloid leukemia (AML) has a dismal prognosis, mostly due to minimal residual disease-driven relapse, making an elimination of persisting therapy-resistant leukemia progenitor/stem cells (LPCs) the main goal for novel therapies. Peptide-
Susanne Jung, Susanne Jung, Susanne Jung, Annika Nelde, Annika Nelde, Yacine Maringer, Yacine Maringer, Monika Denk, Monika Denk, Monika Denk, Lisa Zieschang, Lisa Zieschang, Lisa Zieschang, Christine Kammer, Christine Kammer, Melek Özbek, Melek Özbek, Melek Özbek, Peter Martus, Christopher Hackenbruch, Christopher Hackenbruch, Christopher Hackenbruch, Alexander Englisch, Alexander Englisch, Alexander Englisch, Jonas S. Heitmann, Jonas S. Heitmann, Jonas S. Heitmann, Helmut R. Salih, Helmut R. Salih, Juliane S. Walz, Juliane S. Walz, Juliane S. Walz, Juliane S. Walz   +33 more
doaj   +1 more source

Encapsulation of cisplatin in long-circulating and pH-sensitive liposomes improves its antitumor effect and reduces acute toxicity

International Journal of Nanomedicine, 2012
Elaine A Leite,1,2 Cristina M Souza,3 Álvaro D Carvalho-Júnior,1,2 Luiz GV Coelho,4 Ângela MQ Lana,5 Geovanni D Cassali,3 Mônica C Oliveira11Departamento de Produtos Farmacêuticos, Faculdade de Farm&
Leite EA, Souza CM, Carvalho-Júnior AD, Coelho LG, Lana AM, Cassali GD, Oliveira MC   +6 more
doaj  

EVALUACION ANTITUMORAL Y TOXICOLOGICA DE LOS EXTRACTOS ALCOHOLICOS DE Pedilanthus tithymaloides (L.) Poit. Toxicity studies and an antitumoral evaluation of the alcoholic extracts for P. tithymaloides

Revista Habanera de Ciencias Médicas, 2008
Con el propósito de determinar la posible actividad contra carcinomas que se reporta para la especie P. tithymaloides por la Medicina tradicional, se realizó el estudio de toxicidad y la evaluación antitumoral de los extractos alcohólicos de hojas (IRH ...
Hirán R. Cabrera Suárez, Ana K. Ruiz, María Reyes, Figueroa, . Armando Cuéllar Cuéllar, Yolanda Valdés, Rita M. Pérez Gil   +5 more
doaj  

Evaluación antitumoral y toxicológica de los extractos alcohólicos de Pedilanthus tithymaloides (L.) Poit.

Revista Habanera de Ciencias Médicas, 2008
Con el propósito de determinar la posible actividad contra carcinomas que se reportpara la especie P. tithymaloides por la Medicina tradicional, se realizó el estudio de toxicidad y la evaluación antitumoral de los extractos alcohólicos de hojas (IRH) y ...
Hirán R. Cabrera Suárez, Ana K. Ruiz, María Reyes Figueroa, Armando Cuéllar Cuéllar, Yolanda Valdés, Rita M. Pérez Gil   +5 more
doaj  

Die Beeinflussung des Wachstums des Ehrlich-Ascites-Tumors der Maus durch native und mit ultraviolettem Licht bestrahlte heterologe Desoxyribonucleinsäure

Zeitschrift für Naturforschung B, 1963
1. Deoxyribonuclease activity has been determined by viscosimetry in the serum of the Ehrlich Ascites in the mouse to be equivalent to 2,3 ± 0,7·10-6 g/ml of crystalline beef pancreas DNase. 2. Injections of heterologous deoxyribonucleic acid into the Ehrlich Ascites tumor under specified conditions does not alter tumor development.
Zahn, Rudolf K., Tiesler, Ekkehard
openaire   +2 more sources

Oil-in-water biocompatible microemulsion as a carrier for the antitumor drug compound methyl dihydrojasmonate

International Journal of Nanomedicine, 2015
Gisela Bevilacqua Rolfsen Ferreira da Silva,1 Maria Virginia Scarpa,1 Iracilda Zepone Carlos,2 Marcela Bassi Quilles,2 Raphael Carlos Comeli Lia,3 Eryvaldo Socrates Tabosa do Egito,4 Anselmo Gomes de Oliveira1 1Departamento de Fármacos e ...
Silva GB, Scarpa MV, Carlos IZ, Quilles MB, Lia RC, Egito ES, Oliveira AG   +6 more
doaj  

Efeitos da morfina e metadona sobre o comportamento e crescimento tumoral de camundongos com tumor de Ehrlich [PDF]

, 2021
openaire   +1 more source