Results 21 to 30 of about 611 (136)

Tumor de Klatskin - uma revisão de literatura

Brazilian Journal of Health Review
O colangiocarcinoma hilar, comumente conhecido como tumor de Klatskin, é uma neoplasia rara que acomete a junção dos ductos biliares intra-hepáticos. Sua incidência é baixa, porém seu prognóstico é ruim em um curto período de tempo na maioria dos pacientes afetados.
Daniel Assis Pereira, Fernando Batista Nigri dos Santos, Marcela Magalhães Saldanha, Lígia Regina Bastos Neves, Fábio Fernandes Teixeira   +4 more
openaire   +1 more source

Diagnóstico E Intervenções Curativas E Paliativas Do Colangiocarcinoma Hilar (Tumor De Klatskin)

Revista Científica Multidisciplinar Núcleo do Conhecimento, 2021
Objetivos: Realizar um levantamento de dados da literatura acerca da epidemiologia, fatores de risco, quadro clínico de apresentação e intervenções curativas e paliativas para o colangiocarcinoma hilar ou Tumor de Klatskin. Métodos: A pesquisa foi realizada utilizando a fórmula de busca, elaborada a partir dos descritores “tumor de Klatskin ...
Andresa Mayra de Sousa Melo, Bianca Abreu Giestal Filgueiras, Fernanda Cândido Pereira, Isabela de Oliveira Resende Neves, Isadora Prates de Almeida Lopes Abelha, Mariana de Jesus Oliveira, Rafaela Mancini Carvalho, Raissa Sguizzatto Calderaro, Yuri Dantas Oliveira Silva, Geterson Bezerra Moreira   +9 more
openaire   +1 more source

Validity of Diagnostic Codes and Laboratory Tests to Identify Cholangiocarcinoma and Its Subtypes

Pharmacoepidemiology and Drug Safety, Volume 34, Issue 5, May 2025.
ABSTRACT Background The absence of validated methods to identify cholangiocarcinoma in real‐world data has prevented the conduct of pharmacoepidemiologic studies to evaluate determinants of this malignancy and examine the effectiveness of cholangiocarcinoma treatments.
Nicole D. Ferrante, Rebecca A. Hubbard, Kelley Weinfurtner, Anya I. Mezina, Craig W. Newcomb, Emma E. Furth, Debika Bhattacharya, Basile Njei, Tamar H. Taddei, Amit Singal, Maarouf A. Hoteit, Lesley S. Park, David Kaplan, Vincent Lo Re III   +13 more
wiley   +1 more source

Chemoradiation of locally advanced biliary cancer: A PRISMA‐compliant systematic review

Cancer Medicine, Volume 13, Issue 23, December 2024.
This is a systematic review of the current evidence on “modern” chemoradiation for primary or recurrent unresectable biliary tract cancers. We have critically compared chemoradiation outcomes with those of other treatment options, seeking to determine whether specific chemoradiation modalities provide distinct advantages in terms of treatment efficacy ...
Silvia Bisello, Claudio Malizia, Filippo Mammini, Erika Galietta, Federica Medici, Gian Carlo Mattiucci, Francesco Cellini, Andrea Palloni, Luca Tagliaferri, Gabriella Macchia, Francesco Deodato, Savino Cilla, Giovanni Brandi, Alessandra Arcelli, Alessio G. Morganti   +14 more
wiley   +1 more source

Prevalence and Significance of AGR2 Expression in Human Cancer

Cancer Medicine, Volume 13, Issue 21, November 2024.
ABSTRACT Backround Anterior gradient 2 (AGR2) is a resident endoplasmic reticulum (ER) protein with a vital role in embryonal development, mucus maturation, tissue regeneration, and wound healing. Methods To determine the prevalence and clinical significance of AGR2 expression in cancer, a tissue microarray containing 14,966 tumors from 134 different ...
Nina Schraps, Jacob Constantin Port, Anne Menz, Florian Viehweger, Seyma Büyücek, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Martina Kluth, Claudia Hube‐Magg, Katharina Möller, Viktor Reiswich, Andreas M. Luebke, Patrick Lebok, Sören Weidemann, Guido Sauter, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Stefan Steurer, Baris Mercanoglu, Nathaniel Melling, Thilo Hackert, Eike Burandt, Natalia Gorbokon, Sarah Minner, Till Krech, Florian Lutz   +31 more
wiley   +1 more source

Traqueobroncopatia osteocondroplástica em portador de tumor de Klatskin: relato de caso e revisão da literatura [PDF]

Jornal Brasileiro de Patologia e Medicina Laboratorial, 2008
A traqueopatia osteocondroplastica (TO) e uma desordem idiopatica, incomum, caracterizada pela presenca de nodulos osteocartilaginosos na submucosa das vias aereas, causando rigidez e estreitamento da arvore respiratoria. Afeta principalmente homens acima dos 50 anos com manifestacoes clinicas devidas a obstrucao e/ou a infeccoes locais. Sua patogenese
Faig-Leite, Fabíola Sawaguchi, Faveri, Julio de   +1 more
openaire   +4 more sources

Septin 9 expression regulates ‘don't eat me’ signals and identifies an immune–epithelial class of intrahepatic cholangiocarcinoma

Molecular Oncology, Volume 18, Issue 10, Page 2369-2392, October 2024.
Septin 9 is identified as a regulator of EMT and the host immune response. Intrahepatic cholangiocarcinoma (iCCA) was categorized into two groups: (1) ‘immune–epithelial’, with high expression of septin 9 and ‘don't eat me’ signal genes regulated by IFNγ/STAT1; and (2) ‘mesenchymal–ECM’, with high expression of vimentin, MMP7 and TIMP1.
Ting ting Cai, Christophe Desterke, Juan Peng, Jean Agnetti, Peixuan Song, Dalila Ouazib, Alexandre Dos Santos, Catherine Guettier, Didier Samuel, Ama Gassama‐Diagne   +9 more
wiley   +1 more source

Tumor of Klatskin

Acta Médica del Centro, 2017
Se trata de una paciente femenina de 61 años, con antecedentes patológicos personales de hipertensión arterial y hepatitis viral. Tres días previos al ingreso se le practicó una colangiografía retrógrada por vía endoscópica para la extracción de litiasis
Arletis Ferrer Pérez, Mayelín Casas Padrón, Leonardo Ortiz Díaz, Vivian Díaz de Villegas Reguera, Dianelí Lorely Reyes Hernández, Raunel Batista Hernández, Laide Pino Chávez, Javier Alejandro Comas García   +7 more
doaj  

Efficacy and safety of endoscopic ultrasonography (EUS) hepaticogastrostomy (HGS) versus choledochoduodenostomy (CDS) in ERCP‐failed malignant biliary obstruction: A systematic review and META‐analysis

JGH Open, Volume 8, Issue 10, October 2024.
Abstract Endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard in managing malignant biliary obstruction. The success of ERCP has limitations, whereas surgical biliary bypass and percutaneous transhepatic approaches, as alternative modalities, come with significant costs, longer durations, and higher levels of mortality and ...
Chrisandi Y Rizqiansyah, Putu I D Awatara, Nasim Amar, Cosmas R A Lesmana, Syifa Mustika   +4 more
wiley   +1 more source

CT Texture Analysis of Perihilar Cholangiocarcinoma—Associations With Tumor Grading, Tumor Markers and Clinical Outcome

Cancer Reports, Volume 7, Issue 9, September 2024.
ABSTRACT Background Texture analysis derived from computed tomography (CT) may provide clinically relevant imaging biomarkers associated with tumor histopathology. Perihilar cholangiocarcinoma is a malignant disease with an overall poor prognosis. Aims The present study sought to elucidate possible associations between texture features derived from CT ...
Jakob Leonhardi, Arsen Sabanov, Anne Kathrin Höhn, Robert Sucher, Daniel Seehofer, Matthias Mehdorn, Benedikt Schnarkowski, Sebastian Ebel, Timm Denecke, Hans‐Jonas Meyer   +9 more
wiley   +1 more source