Results 91 to 100 of about 48,342,326 (223)

Tumor de Wilms' na criança: revisão de 38 casos.

Acta Médica Portuguesa, 1991
Analysis of the incidence of the Nephroblastoma and of its clinic, echographic and radiologic aspects. Review of 38 cases handled in the Pediatric Surgery Service of Santa Maria Hospital between January 1960 and January 1987.
M J Leal, M Gonçalves, J M da Silva, J R de Oliveira   +3 more
doaj   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

Anaplastic Wilms’ Tumor Mimicking a Rhabdoid Tumor: A Diagnostic Challenge: Wilms’ Tumor Mimicking a Rhabdoid Tumor

, 2021
Rhabdoid tumor of the kidney (RTK) mimics other renal tumors histologically, but a rhabdoid tumor mimicking an anaplastic Wilms’ tumor has been rarely reported.
Anand , Amrita, Agarwal , Kiran, Suman, Neha, Singh , Smita   +3 more
core   +1 more source

Wilms’ Tumor in children treated at the provincial pediatric hospital of Holguín

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: Wilms’ tumor is a malignant neoplasia whose origin has been attributed to disorders in the renal histogenesis. It has been described as the fifth malignant neoplasia in pediatrics; it is the commonest renal tumor.Objective: to describe a ...
Onelis Góngora-Gómez, Juan Pablo Carballido-Sánchez, Yadnil Elizabeth Gómez-Vázquez, Rosalí Bauta-Milord, Adrián Ramírez-Quintana   +4 more
doaj  

Wt1 Is Required for the Regression of Müllerian Ducts in Male Mice by Inducing Wif1 and Osx Expression

Cell Proliferation, EarlyView.
Wt1 expressed in the MD mesenchyme promotes MD regression by inducing Wif1 and Osx transcription. In male mice, mesenchyme‐specific inactivation of Wt1 results in MD retention. ABSTRACT In mammals, Müllerian ducts (MDs) are the precursors of the female reproductive tract which regress in males during embryonic development.
Min Chen, Xin Qi, Shanshan Qin, Jia Kang, Changhuo Cen, Miao Guo, Yang Gao, Mengyue Wang, Jiayi Li, Xiuhong Cui, Yanbo Wang, Lan Zhu, Fei Gao   +12 more
wiley   +1 more source

Quantitative RT-PCR-based miRNA profiling of blastemal Wilms’ tumors

, 2018
A blastemás Wilms-tumorok kedvezőtlen prognózist mutatnak a kemoterápiára való alacsony érzékenység miatt. Célunk a kísérlet során az volt, hogy hozzájáruljunk a betegség miRNSprofilozásához és megvizsgáljuk, hogy felhasználhatunk-e FFPE mintákat miRNS-
Berki, Zsanett
core  

Heterogeneity of disease classified as stage III in Wilms tumor: a report from the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP).

, 2012
PURPOSE: We analyzed whether the prognosis can differ among Wilms tumors (WT) labeled as Stage III according to currently adopted classification systems.
Nantron M, Provenzi M, AIEOP Wilms Tumor Working Group, PESSION, ANDREA, Bianchi M, D'Angelo P, Gandola L, Indolfi P, Di Cataldo A, Piva L, Terenziani M, Marchianò A, Fossati Bellani F, Collini P, Catania S, Spreafico F   +15 more
core   +1 more source

HMGA2 is a highly sensitive marker for DICER1‐related tumours

Histopathology, EarlyView.
Aims DICER1 is a microRNA biogenesis enzyme that, when mutated, results in a rewiring of the transcriptome. Germline pathogenic variants (PVs) in DICER1 result in DICER1‐related tumour predisposition (DRTP) characterized by 30 or more different, generally rare, paediatric or adolescent‐onset tumours.
Paul S. Thorner, Anne‐Laure Chong, Naciba Benlimane, Lili Fu, Marc R. Fabian, William D. Foulkes   +5 more
wiley   +1 more source

Synchronous bilateral Wilms tumor: A report from the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP).

, 2013
BACKGROUND: The optimal management of bilateral Wilms tumor (BWT) is challenging, and their survival is lower than for unilateral tumors. This report discusses a large series of BWTs treated in Italy in the last 2 decades.
Di Martino M, CECCHETTO, GIOVANNI, Jenkner A, Bianchi M, On behalf of the AIEOP Wilms Tumor Working Group, Serra A, Crocoli A, Pession A, D'Angelo P, BISOGNO, GIANNI, Gandola L, Inserra A, Conte M, Indolfi P, Terenziani M, Collini P, Biasoni D, Spreafico F   +17 more
core   +1 more source

WTAP‐mediated m6A RNA methylation promotes diabetic foot ulcer healing under negative pressure wound therapy

Journal of Diabetes Investigation, EarlyView.
NPWT significantly increases the suppressed WTAP and m6A levels in DFU patients, correlating directly with better 4‐week healing outcomes. In vitro, negative pressure reverses high‐glucose‐induced WTAP downregulation, restoring the cell proliferation and migration necessary for wound repair.
Yutong Li, Wenhua Chen, Jianhao Lu, Xiaoyue Lin, Ying Tang, Jiaxu Li, Mingwei Chen   +6 more
wiley   +1 more source