Results 131 to 140 of about 3,155,046 (320)

Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100

Mediators of Inflammation, 2015
We show that galactomannan, a polysaccharide consisting of a mannose backbone with galactose side groups present on the cell wall of several fungi, induces a reprogramming of the inflammatory response in human macrophages through dectin-1 receptor.
Víctor Toledano, Enrique Hernández-Jiménez, Carolina Cubillos-Zapata, Marta Flandez, Enrique Álvarez, Aníbal Varela-Serrano, Ramón Cantero, Gema Valles, Francisco García-Rio, Eduardo López-Collazo   +9 more
doaj   +1 more source

Human Dendritic Cells: Their Heterogeneity and Clinical Application Potential in Cancer Immunotherapy

Frontiers in Immunology, 2019
Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve T cell activation and effector differentiation. They are, likewise, involved in the induction and maintenance of immune tolerance in homeostatic conditions ...
Thiago A. Patente, Mariana P. Pinho, Aline A. Oliveira, Gabriela C. M. Evangelista, Patrícia C. Bergami-Santos, José A. M. Barbuto, José A. M. Barbuto   +6 more
doaj   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Novel approach to identify putative Epstein–Barr–virus microRNAs regulating host cell genes with relevance in tumor biology and immunology [PDF]

, 2022
Simon Jasinski‐Bergner, Juliane Blümke, Marcus Bauer, Saskia Luise Skiebe, Ofer Mandelboim, Claudia Wickenhauser, Barbara Seliger   +6 more
openalex   +1 more source

A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang, Da Lin, Dongyuan Liu, Dongxu Zhang, Hao Wang   +4 more
wiley   +1 more source

Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion

Journal for ImmunoTherapy of Cancer, 2022
Carl G Figdor, I Jolanda M de Vries, Camille Le Gall, Anna Cammarata, Lukas de Haas, Iván Ramos-Tomillero, Jorge Cuenca-Escalona, Kayleigh Schouren, Zacharias Wijfjes, Anouk M D Becker, Johanna Bödder, Yusuf Dölen, Georgina Flórez-Grau, Martijn Verdoes   +13 more
doaj   +1 more source

Tumor Immunology, Immunotherapy and Cancer Vaccines [PDF]

, 1997
Jonathan A. Ledermann
openalex   +1 more source

Corrigendum: Lipid metabolism in tumor immunology and immunotherapy. [PDF]

Front Oncol, 2023
Duong LK, Corbali HI, Riad TS, Ganjoo S, Nanez S, Voss T, Barsoumian HB, Welsh J, Cortez MA.   +8 more
europepmc   +1 more source

Tumor immunology and cancer immunotherapy: summary of the 2013 SITC primer

Journal of Immunotherapy for Cancer, 2014
Knowledge of the basic mechanisms of the immune system as it relates to cancer has been increasing rapidly. These developments have accelerated the translation of these advancements into medical breakthroughs for many cancer patients.
R. Raval, A. Sharabi, A. Walker, C. Drake, Padmanee Sharma   +4 more
semanticscholar   +1 more source