Results 201 to 210 of about 3,283,768 (383)

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

Advanced Functional Materials, EarlyView.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen, Pengfei Zhang, Fathima Shana Pattar Kadavan, Zhaoning Xu, Tien Thanh Nguyen, Wenshao Li, Manh Tuong Nguyen, Chung Kim Nguyen, Duy Quang Pham, Thi Giang Tuyet Pham, Andrew Hayles, Markos Negash Alemie, Jitraporn Vongsvivut, Vincent Chan, Stephen Peter Kidd, Yunpeng Zhao, Krasimir Vasilev, Vi Khanh Truong   +17 more
wiley   +1 more source

MHC class I/II deficient NOG mice are useful for analysis of human T/B cell responses for human tumor immunology research [PDF]

, 2013
Tomonori Yaguchi, Asuka Kobayashi, Ikumi Katano, Yuyo Ka, Mamoru Ito, Yutaka Kawakami   +5 more
openalex   +1 more source

Biocompatibility of Water‐Dispersible Pristine Graphene and Graphene Oxide Using a Close‐to‐Human Animal Model: A Pilot Study on Swine

Advanced Healthcare Materials, EarlyView.
Graphene‐based materials are attracting considerable interest for biomedical applications. Analysis of their biocompatibility is required before their clinical translation, and swine represents an excellent close‐to‐human model. This study evaluates the toxicological and immunological impact of pristine graphene and graphene oxide through a compendium ...
Paola Nicolussi, Giovannantonio Pilo, Maria Giovanna Cancedda, Guotao Peng, Ngoc Do Quyen Chau, Alejandro De la Cadena, Renzo Vanna, Yarjan Abdul Samad, Tanweer Ahmed, Jeremia Marcellino, Giuseppe Tedde, Linda Giro, Acelya Ylmazer, Federica Loi, Gavina Carta, Loredana Secchi, Silvia Dei Giudici, Simona Macciocu, Dario Polli, Yuta Nishina, Ciriaco Ligios, Giulio Cerullo, Andrea Ferrari, Alberto Bianco, Bengt Fadeel, Giulia Franzoni, Lucia Gemma Delogu   +26 more
wiley   +1 more source

DEMO: Dose Exploration, Monitoring, and Optimization Using a Biological Mediator for Clinical Outcomes [PDF]

arXiv
Phase 1-2 designs provide a methodological advance over phase 1 designs for dose finding by using both clinical response and toxicity. A phase 1-2 trial still may fail to select a truly optimal dose. because early response is not a perfect surrogate for long term therapeutic success.
arxiv  

Tumor Immunology: Multidisciplinary Science Driving Basic and Clinical Advances [PDF]

, 2013
Bridget P. Keenan, Elizabeth M. Jaffee, Todd D. Armstrong   +2 more
openalex   +1 more source

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

Advanced Healthcare Materials, EarlyView.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden, Raquel Alonso‐Román, Johannes Stallhofer, Mark S. Gresnigt, Bernhard Hube, Alexander S. Mosig   +5 more
wiley   +1 more source

PENGARUH KOMBINASI CYCLOPHOSPHAMIDE - TRANSFER FACTOR TERHADAP SKOR SEL T CD4+ PADA ADENOCARSINOMA MAMMAE MENCIT C3H [PDF]

, 2011
Background : Transfer factor are extracts from Colostrum, which is considered as an immunostimulant oligoribonukleotida for alternative therapies. Breast cancer patients will experience a decline in the immune system.
Shodiq, M Ali
core  

Radiotherapy and immunology

Journal of Experimental Medicine
The majority of cancer patients receive radiotherapy. Wang et al. review preclinical and clinical data related to the importance of immune responses to radiotherapy-induced anti-tumor effects, as well as blockade of immune checkpoints PD-1/PD-L1 and/or ...
Liangliang Wang, C. Lynch, S. Pitroda, András Piffkó, Kaiting Yang, Amy K Huser, H. Liang, R. Weichselbaum   +7 more
semanticscholar   +1 more source

A Novel 3D High‐Throughput Phenotypic Drug Screening Pipeline to Identify Drugs with Repurposing Potential for the Treatment of Ovarian Cancer

Advanced Healthcare Materials, EarlyView.
Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia, Amy L. Wilson, Brittany R. Doran, Jennie Do, Amelia Matthews, Gwo Y. Ho, Magdalena Plebanski, Thomas W. Jobling, Andrew N. Stephens, Maree Bilandzic   +9 more
wiley   +1 more source

Tumor Immunology, toward a Success Story? [PDF]

, 2015
Catheriné Sautès-Fridman
openalex   +1 more source