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The Indian Journal of Pediatrics, 2012
Tumor lysis syndrome (TLS) refers to the constellation of deranged metabolic state, characterized by hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia, and/or azotemia, secondary to rapid breakdown of tumor cells. It is a life threatening emergency that typically follows administration of chemotherapy or may be spontaneous.
Aruna, Rajendran +3 more
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Tumor lysis syndrome (TLS) refers to the constellation of deranged metabolic state, characterized by hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia, and/or azotemia, secondary to rapid breakdown of tumor cells. It is a life threatening emergency that typically follows administration of chemotherapy or may be spontaneous.
Aruna, Rajendran +3 more
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Medical and Pediatric Oncology, 1979
AbstractRapid tumor lysis may produce acute complications including systemic metabolic disturbances and hemorrhage in sites involved by tumor. We have observed two cases of acute pancreatitis induced by the lysis of lymphoma that involved the pancreas. This previously unreported cause of pancreatitis must be added to the list of potential complications
R J, Spiegel, I T, Magrath
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AbstractRapid tumor lysis may produce acute complications including systemic metabolic disturbances and hemorrhage in sites involved by tumor. We have observed two cases of acute pancreatitis induced by the lysis of lymphoma that involved the pancreas. This previously unreported cause of pancreatitis must be added to the list of potential complications
R J, Spiegel, I T, Magrath
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Critical Care Nurse, 2022
Background Tumor lysis syndrome is a life-threatening oncologic emergency in adult and pediatric patients with hematologic cancer. It occurs most often in malignancies with rapid cell turnover and large tumor burden, but its incidence has risen in solid tumors.
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Background Tumor lysis syndrome is a life-threatening oncologic emergency in adult and pediatric patients with hematologic cancer. It occurs most often in malignancies with rapid cell turnover and large tumor burden, but its incidence has risen in solid tumors.
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Seminars in Thrombosis and Hemostasis, 2007
Tumor lysis syndrome (TLS) is an important metabolic disorder frequently encountered in the management of a variety of cancers including lymphoma, leukemia, and neuroblastoma. Delayed recognition can result in a variety of biochemical abnormalities resulting in life-threatening complications such as renal failure, arrhythmias, and seizures ...
Ramon V, Tiu +3 more
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Tumor lysis syndrome (TLS) is an important metabolic disorder frequently encountered in the management of a variety of cancers including lymphoma, leukemia, and neuroblastoma. Delayed recognition can result in a variety of biochemical abnormalities resulting in life-threatening complications such as renal failure, arrhythmias, and seizures ...
Ramon V, Tiu +3 more
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Current understanding of tumor lysis syndrome
Hematological Oncology, 2019Tumor lysis syndrome (TLS) is an oncologic emergency from the intracellular release of material in lysing malignant cells. The earlier it is treated, the less likely it is to be harmful to an individual and spread through the body.
Benjamin Rahmani +6 more
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Tumor Lysis Syndrome in Solid Tumors
Supportive Cancer Therapy, 2005Tumor lysis syndrome (TLS) consists of acute hyperuricemic nephropathy, hyperphosphatemia, hypocalcemia, hyperkalemia, and increased serum creatinine. It can be part of the disease presentation, especially in aggressive hematologic malignancies, or a part of the chemotherapy response. There are relatively few reports of TLS in solid tumors.
Frank E, Mott +3 more
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Seminars in Oncology Nursing, 1999
To review the pathophysiology, clinical manifestations, and management of tumor lysis syndrome.Published articles, case reports, and book chapters on tumor lysis syndrome.Tumor lysis syndrome is a very serious and sometimes life-threatening complication of cancer treatment. Identification of patients at risk and initiation of preventative interventions
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To review the pathophysiology, clinical manifestations, and management of tumor lysis syndrome.Published articles, case reports, and book chapters on tumor lysis syndrome.Tumor lysis syndrome is a very serious and sometimes life-threatening complication of cancer treatment. Identification of patients at risk and initiation of preventative interventions
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Tumor lysis syndrome in elderly
Critical Reviews in Oncology/Hematology, 2007The majority of cancers occur in adults over the age of 65, with about 70% of all cancer deaths in this population. Tumor lysis syndrome (TLS) is a complication of hematological and others malignancies, caused by massive tumor cell lysis due to chemotherapy, immunotherapy, radiotherapy.
PUMO V, SCIACCA D, MALAGUARNERA, Mariano
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Seminars in Hematology, 2001
Tumor lysis syndrome (TLS) is a constellation of metabolic disturbances observed in tumors with high cell turnover. It is associated with significant morbidity and mortality. TLS is characterized by the increased release of intracellular contents (uric acid, potassium, phosphorus) into the extracellular compartment, which can overwhelm the body's ...
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Tumor lysis syndrome (TLS) is a constellation of metabolic disturbances observed in tumors with high cell turnover. It is associated with significant morbidity and mortality. TLS is characterized by the increased release of intracellular contents (uric acid, potassium, phosphorus) into the extracellular compartment, which can overwhelm the body's ...
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Managing Tumor Lysis Syndrome in the Era of Novel Cancer Therapies
Journal of the Advanced Practitioner in Oncology, 2017Tumor lysis syndrome (TLS) is a potentially life-threatening emergency that can develop rapidly after the release of intracellular contents from lysed malignant cells.
A. McBride +4 more
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