A lactate related signature for predicting prognosis and tumor microenvironment in lung adenocarcinoma. [PDF]
Wang Y, Li H, Chen C, Yu H, Xu L.
europepmc +1 more source
This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An+8 more
wiley +1 more source
Editorial: Immune cell therapy approaches targeting tumor microenvironment. [PDF]
Patnaik SK, Kalathil SG.
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Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan+13 more
wiley +1 more source
Aerobic exercise-induced lactate production: a novel opportunity for remodeling the tumor microenvironment. [PDF]
Zhou X+5 more
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Tumor Microenvironment‐responsive Nanocatalyst for Targeted Chemodynamic Cancer Therapy
An Tumor microenvironment‐responsive nanocatalyst system composed of PLGA‐encapsulated Ca–Fe peroxide and polyarginine enables sustainable Fenton reaction in tumors. Low levels of H2O2 (50–100 µm) initiate the nanoparticle degradation, while polyarginine‐derived nitric oxide accelerates Fe3+ reduction, leading to self‐amplifying •OH generation for ...
Jun Ma, Jingjing Qiu, Shiren Wang
wiley +1 more source
The Role of Viruses in the Glioma Tumor Microenvironment: Immunosuppressors or Primers for Anti-Tumor Immunity? [PDF]
Hudson AJ+4 more
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Losartan as a mechanotherapeutic adjuvant: Remodeling the breast tumor microenvironment to improve treatment efficacy. [PDF]
Dwairy M+3 more
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Role of the RAB27/SYTL Axis in Tumor Microenvironment Construction. [PDF]
Tanaka M, Nakamura T.
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Tumor suppressor genes in the tumor microenvironment.
Tabanifar B, Lau H, Sabapathy K.
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