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Role of microplastics in the tumor microenvironment (Review). [PDF]

Oncol Lett
Chen Y, Zhang Z, Ji K, Zhang Q, Qian L, Yang C.   +5 more
europepmc   +1 more source

Gemcitabine: immunomodulatory or immunosuppressive role in the tumor microenvironment. [PDF]

Front Immunol
Nemati M, Hsu CY, Nathiya D, Kumar MR, Oghenemaro EF, Kariem M, Kaur P, Bhanot D, Hjazi A, Azam Saedi T.   +9 more
europepmc   +1 more source

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The tumor microenvironment

Surgical Oncology, 2012
The concept of the tumor microenvironment, developed from Paget's "seed and soil" theory is made up of the cancer cells, the stromal tissue, and the extracellular matrix. In this mini-review, each of the components of this dynamic network will be examined.
Cynthia E. Weber, Paul C. Kuo
openaire   +3 more sources

Eosinophils in the Tumor Microenvironment

2020
Eosinophils are rare blood-circulating and tissue-infiltrating immune cells studied for decades in the context of allergic diseases and parasitic infections. Eosinophils can secrete a wide array of soluble mediators and effector molecules, with potential immunoregulatory activities in the tumor microenvironment (TME).
Mattei, Fabrizio, Andreone, Sara, Marone, Giancarlo, Gambardella, Adriana Rosa, Loffredo, Stefania, Varricchi, Gilda, Schiavoni, Giovanna   +6 more
openaire   +5 more sources

The Tumor Microenvironment

2010
Recent advances in stem cell and developmental neurobiology have uncovered new perspectives from which we investigate various forms of cancer. Specifically, the hypothesis at tumors are comprised of a subpopulation of malignant cells similar to stem cells is of great interest to scientists and clinicians and has been dubbed the cancer stem cell ...
Lissa C. Baird, Alexey V. Terskikh
openaire   +3 more sources

Fibroblasts in the Tumor Microenvironment

2020
The implications of a tumor microenvironment in cancer initiation and progression have drawn interest in recent years. Within the tumor stroma, fibroblasts represent a predominant cell type and are responsible for the majority of extracellular components within the tumor microenvironment, such as matrix and soluble factors.
Truffi M., Sorrentino L., Corsi F.
openaire   +4 more sources

Leptin in Tumor Microenvironment

2020
Leptin is a hormone that plays a major role as mediator of long-term regulation of energy balance, suppressing food intake, and stimulating weight loss. More recently, important physiological roles other than controlling appetite and energy expenditure have been suggested for leptin, including neuroendocrine, reparative, reproductive, and immune ...
Angelucci, A, Clementi, L, Alesse, E
openaire   +4 more sources

CCL2 in the Tumor Microenvironment

2021
The C-C motif chemokine ligand 2 (CCL2) is a crucial mediator of immune cell recruitment during microbial infections and tissue damage. CCL2 is also frequently overexpressed in cancer cells and other cells in the tumor microenvironment, and a large body of evidence indicates that high CCL2 levels are associated with more aggressive malignancies, a ...
Tracy Lynn O'Connor, Mathias Heikenwalder   +1 more
openaire   +3 more sources