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Role of lipopolysaccharide and tumor necrosis factor-alpha in induction of hepatocyte necrosis
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1995The occurrence of acute hepatic failure during systemic inflammatory response syndrome (SIRS) is related to the extent of hepatocyte (HC) damage and cell death resulting from necrosis or apoptosis. We hypothesized that proinflammatory mediators such as lipopolysaccharide (LPS) and tumor necrosis factor-alpha (TNF-alpha) can, either directly or ...
J H, Wang +3 more
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Sensors and Actuators B: Chemical, 2015
Abstract Tumor necrosis factor (TNF)-α promotes rheumatoid arthritis (RA) symptoms, including inflammation and bone erosion. The role of TNF-α in RA is considered to be complex because cytokine is responsible for a wide-range of functions, such as activation of immune cells, stimulation of osteoclast differentiation, and induction of cellular ...
Ugurag, Deniz +4 more
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Abstract Tumor necrosis factor (TNF)-α promotes rheumatoid arthritis (RA) symptoms, including inflammation and bone erosion. The role of TNF-α in RA is considered to be complex because cytokine is responsible for a wide-range of functions, such as activation of immune cells, stimulation of osteoclast differentiation, and induction of cellular ...
Ugurag, Deniz +4 more
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The regulation of circadian clock by tumor necrosis factor alpha
Cytokine & Growth Factor Reviews, 2019All organisms display circadian rhythms which are under the control of the circadian clock located in the hypothalamus at the suprachiasmatic nucleus, (SCN). The circadian rhythms allow individuals to adjust their physiological activities and daily behavior for the diurnal changes in the living environment. To achieve these, all metabolic processes are
Mustafa Gokhan, Ertosun +2 more
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Cardiodepression by tumor necrosis factor-alpha.
European cytokine network, 1999Cardiodepressant effects of tumor necrosis factor-alpha (TNF-alpha have been documented in numerous experimental settings in vivo and in vitro. In vivo administration of TNF-alpha mimicks the cardiovascular pattern of sepsis including septic cardiomyopathy.
U, Müller-Werdan +2 more
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[Tumor necrosis factor alpha. Biological aspects].
Giornale italiano di chemioterapia, 1989Human Tumor Necrosis Factor-alpha (TNF-alpha) is a multifaceted cytokine mainly produced by activated monocytes or macrophages. Several recent studies have shown that TNF-alpha can exert a variety of in vitro and in vivo effects including: modulation of normal and malignant haemopoiesis, antineoplastic activity, activation of neutrophils, induction of ...
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[Tumor necrosis factor-alpha (cachectin)].
Revista clinica espanola, 1989Tumor necrosis factor (TNF) is liberated by macrophages in response to infection. It has different biological effects, namely cytotoxicity on some tumor cell lines, anorexia, hyperlipidemia, and decreases in protein synthesis. It favors immunological responses and produces necrosis of certain tumors.
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Tumor Necrosis Factor Alpha: Implications of Anesthesia on Cancers
Cancers, 2023Zhi-Fu Wu +2 more
exaly
American Journal of Obstetrics and Gynecology, 2005
Jennifer Donnelly +7 more
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Jennifer Donnelly +7 more
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Effect of tumor necrosis factor alpha on mitogen-activated human B cells.
Journal of Experimental Medicine, 1987Kehrl J H, Fauci A S
exaly