Results 271 to 280 of about 314,005 (303)

Engineering a Synthetic Ligand for Tumor Necrosis Factor–Alpha

Bioconjugate Chemistry, 2011
One approach to prepare protein binding ligands is to join two low-affinity ligands that bind different sites on the target protein to create a high-affinity bivalent ligand. This typically requires some knowledge of the ligand binding site and requires exquisite orientation of the ligands in order to achieve maximum binding affinity. Here, we explored
Nidhi, Gupta, Paul E, Belcher, Stephen Albert, Johnston, Chris W, Diehnelt   +3 more
openaire   +2 more sources

Cardiodepression by tumor necrosis factor-alpha.

European cytokine network, 1999
Cardiodepressant effects of tumor necrosis factor-alpha (TNF-alpha have been documented in numerous experimental settings in vivo and in vitro. In vivo administration of TNF-alpha mimicks the cardiovascular pattern of sepsis including septic cardiomyopathy.
U, Müller-Werdan, H, Engelmann, K, Werdan   +2 more
openaire   +1 more source

Production of Tumor Necrosis Factor-Alpha in Patients on Hemodiafiltration

Nephron, 2008
The systemic production of tumor necrosis factor (TNF)-α was evaluated in uremic patients before and after hemodiafiltration (HDF) and paired filtration dialysis (PFD) and in the interdialytic period. Both HDF and PFD were performed using polysulfone dialyzers with either standard or ultrapure dialysis fluid.
C, Tetta, T, Fidelio, C, Licata, L, Iacono, G, Sancipriano, L, Biancone, R, Ragni, G, Segoloni, G, Camussi   +8 more
openaire   +2 more sources

Piezoelectric biosensor for the determination of Tumor Necrosis Factor Alpha

Talanta, 2018
Tumor Necrosis Factor Alpha (TNFα) is an important marker of inflammatory processes in human body. In the current healthcare, determination of TNFα blood or plasma level is done by Enzyme Linked Immuno-Sorbent Assay (ELISA) as a primary choice method. Piezoelectric immunosensors are analytical platform recording affinity interactions on their surface ...
openaire   +2 more sources

Secretion of tumor necrosis factor alpha by testicular macrophages

Journal of Reproductive Immunology, 1993
While it has been shown that culture medium from testicular macrophages can influence testosterone production when added to Leydig cells, the identity of the factor(s) responsible for this activity remains unknown. Since tumor necrosis factor alpha (TNF alpha) has been shown to be capable of influencing testosterone production by Leydig cells, a series
openaire   +2 more sources

[Tumor necrosis factor-alpha (cachectin)].

Revista clinica espanola, 1989
Tumor necrosis factor (TNF) is liberated by macrophages in response to infection. It has different biological effects, namely cytotoxicity on some tumor cell lines, anorexia, hyperlipidemia, and decreases in protein synthesis. It favors immunological responses and produces necrosis of certain tumors.
openaire   +1 more source

Tumor Necrosis Factor Alpha

2012
Adamantios Arampatzis, Lida Mademli, Thomas Reilly, Mike I. Lambert, Laurent Bosquet, Jean-Paul Richalet, Thierry Busso, Bertrand Mettauer, Stéphane Gréciano, Bernard Geny, Faidon Magkos, Beat Knechtle   +11 more
openaire   +1 more source

Obesity, tumor necrosis factor-alpha and tumor necrosis factor-alpha −308 polymorphism in normal pregnancy

American Journal of Obstetrics and Gynecology, 2005
Jennifer Donnelly, Sharon Cooley, Joanna Balding, Ciaran Murphy, Tom Walsh, Owen Smith, Michael Geary, Corrina M.C. Mahon   +7 more
openaire   +1 more source

<p>Tumor Necrosis Factor Alpha-Induced Proteins in Malignant Tumors: Progress and Prospects</p>

OncoTargets and Therapy, 2020
Fang Guo, Yuan Yuan
exaly  

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.

Journal of Experimental Medicine, 1991
Elizabeth P Sampaio, Euzenir Nunes Sarno, Z A Cohn   +2 more
exaly