Results 61 to 70 of about 648,894 (406)
The journals of gerontology. Series A, Biological sciences and medical sciences, 2002 BACKGROUND A decline in muscle mass and muscle strength characterizes normal aging. As clinical and animal studies show a relationship between higher cytokine levels and low muscle mass, the aim of this study was to investigate whether markers of ...
M. Visser +7 more
semanticscholar +1 more source
Tumor Necrosis Factor Alpha in Amyotrophic Lateral Sclerosis: Friend or Foe?
Cells, 2021 Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a massive neuroinflammatory reaction, which plays a key role in the progression of the disease.
Giulia Guidotti +3 more
doaj +1 more source
Vascular network remodeling via vessel cooption, regression and growth in tumors [PDF]
J. Theor. Biol. 241, 903 (2006), 2005 The transformation of the regular vasculature in normal tissue into a highly inhomogeneous tumor specific capillary network is described by a theoretical model incorporating tumor growth, vessel cooption, neo-vascularization, vessel collapse and cell death. Compartmentalization of the tumor into several regions differing in vessel density, diameter and
arxiv +1 more source
Harnessing tumor necrosis factor alpha to achieve effective cancer immunotherapy [PDF]
, 2021 Tumor necrosis factor alpha (TNFα) is a pleiotropic cytokine known to have contradictory roles in oncoimmunology. Indeed, TNFα has a central role in the onset of the immune response, inducing both activation and the effector function of macrophages ...
Bruni, Sofia +4 more
core +1 more source
Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition.
New England Journal of Medicine, 2005 BACKGROUND A substantial number of patients with rheumatoid arthritis have an inadequate or unsustained response to tumor necrosis factor alpha (TNF-alpha) inhibitors.
M. Genovese +13 more
semanticscholar +1 more source
Machine Learning Based Radiomics for Glial Tumor Classification and Comparison with Volumetric Analysis [PDF]
arXiv, 2022 Purpose; The purpose of this study is to classify glial tumors into grade II, III and IV categories noninvasively by application of machine learning to multi-modal MRI features in comparison with volumetric analysis. Methods; We retrospectively studied 57 glioma patients with pre and postcontrast T1 weighted, T2 weighted, FLAIR images, and ADC maps ...
arxiv
Journal of Experimental Medicine, 1991 Thalidomide selectively inhibits the production of human monocyte tumor necrosis factor alpha (TNF-alpha) when these cells are triggered with lipopolysaccharide and other agonists in culture. 40% inhibition occurs at the clinically achievable dose of the
E. Sampaio +4 more
semanticscholar +1 more source
Segmental vitiligo after infliximab use for rheumatoid arthritis - A case report [PDF]
Anais Brasileiros de Dermatologia, 2014 The tumor necrosis factor alpha is a cytokine related to immune and inflammatory processes by acting on different parts of the body. It is secreted by several cell types including macrophages, lymphocytes, monocytes, neutrophils, dendritic cells, among ...
Clarissa Luiza Dalla Bernardina Carvalho +1 more
doaj +1 more source
Adults with major depression who are suicidal and those who aren't have different cytokines and lipid profiles. [PDF]
, 2022 OBJECTIVES: We tested whether Tumor necrosis factor-alpha, Interlukin-1β, and lipid profile might be associated with suicide attempts in adult patients with major depression.
arlene gitomer
core +1 more source
Sinusitis in patients on tumor necrosis factor alpha inhibitors [PDF]
International Forum of Allergy & Rhinology, 2016 BackgroundTumor necrosis factor alpha (TNF‐α) inhibitors have revolutionized treatment of many inflammatory diseases. Sinusitis after initiation of TNF‐α inhibitors has been observed, but has not been well described in the literature. We aim to characterize the clinical features of sinusitis in patients on anti‐TNF‐α therapy.MethodsThis is a ...
Adam Honeybrook +4 more
openaire +3 more sources