Results 21 to 30 of about 604,511 (258)
Anti tumor necrosis factor induced focal myositis
Proceedings of Singapore Healthcare, 2022 Tumour necrosis factor inhibitors (TNFis) can trigger autoantibody formation and, in a small proportion of patients, result in symptomatic autoimmune diseases, including polymyositis and dermatomyositis. Focal myositis presents with localized muscle pain
Adrian Mark Masnammany +3 more
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Tumor Necrosis Factor and Tuberculosis [PDF]
Journal of Investigative Dermatology Symposium Proceedings, 2007 Tumor necrosis factor (TNF) plays a major role in the initial and long-term control of tuberculosis. The mechanisms by which this cytokine contributes to the control of Mycobacterium tuberculosis infection are numerous and therefore difficult to dissect. TNF is important in macrophage activation as well as cell recruitment to the site of infection.
Lin, Philana Ling +3 more
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Neural Regeneration Research, 2019 Due to the aging of the population and despite the enormous scientific effort, Alzheimer’s disease remains one of the biggest medical and pharmaceutical challenges in current medicine.
Sophie Steeland +1 more
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Tumor necrosis factor as a pharmacological target [PDF]
Molecular Biotechnology, 2004 As indicated by its name, tumor necrosis factor (TNF), cloned in 1985, was originally described as a macrophage-derived endogenous mediator that can induce hemorrhagic necrosis of solid tumors and kill some tumor cell lines in vitro. Unfortunately, its promising use as an anticancer agent was biased by its toxicity, which was clear soon from the first ...
Ghezzi, Pietro, Cerami, Anthony
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Scientific Reports, 2017 Tumor necrosis factor receptor 2 (TNFR2) is known to mediate immune suppression and tissue regeneration. Interestingly, the transmembrane form of tumor necrosis factor (tmTNF) is necessary to robustly activate TNFR2. To characterize the stoichiometry and
Roman Fischer +7 more
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Nature Communications, 2018 Anti-TNF therapy has improved the treatment of inflammatory disease but can predispose to infection and malignancy. Here the authors show an anti-TNF biologic peptide that functionally and selectively targets the TNF-p38 pathway in multiple models of ...
Violet R. Mukaro +9 more
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Iatreia, 2018 Tumor necrosis factor receptor periodic syndrome (TRAPS) is characterized by episodes of fever of more than 10 days of duration, migratory myalgias, pseudocellulitis, abdominal pain and bipalpebral edema.
Moreno Zuluaga, Catalina +1 more
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Practical Laboratory Medicine, 2019 Objective: Soluble Tumor Necrosis Factor Receptor II (sTNFR2) is used as a biomarker to study cardiovascular disease (CVD) in diverse populations. TNF inhibitors (TNFi's) are a common treatment for inflammatory conditions. The objective of this study was
Nicole Yang +8 more
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Listeria Cerebritis with Tumor Necrosis Factor Inhibition
Case Reports in Infectious Diseases, 2020 Background. Listeria monocytogenes is historically a central nervous system pathogen of consideration in the very young, very old, and immune suppressed. Diagnosis of Listeria is based on positive bodily fluid culture or PCR testing.
Eileen Reilly, Justin Hwang
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miR-29a suppresses MCF-7 cell growth by downregulating tumor necrosis factor receptor 1
Tumor Biology, 2017 Tumor necrosis factor receptor 1 is the main receptor mediating many tumor necrosis factor-alpha–induced cellular events. Some studies have shown that tumor necrosis factor receptor 1 promotes tumorigenesis by activating nuclear factor-kappa B signaling ...
Yiling Zhao +7 more
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