Results 311 to 320 of about 725,440 (353)
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Tumor Necrosis Factor and Obesity
Annals of Internal Medicine, 1989Excerpt To the Editor:Although its role is not fully known, tumor necrosis factor (TNF) or cachectin would appear to be involved in determining nutritional status.
S, Chollet-Martin +3 more
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Seminars in Surgical Oncology, 1989
AbstractTumor necrosis factor (TNF) is a well‐described and characterized cytokine which can be elicited in the intact animal by endotoxin. This factor produces necrosis of subcutaneous tumors in the classic model: Meth A sarcoma in the Balb C mouse. It has been shown to be cytostatic or cytotoxic for a variety of human cancer cell lines, as well as to
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AbstractTumor necrosis factor (TNF) is a well‐described and characterized cytokine which can be elicited in the intact animal by endotoxin. This factor produces necrosis of subcutaneous tumors in the classic model: Meth A sarcoma in the Balb C mouse. It has been shown to be cytostatic or cytotoxic for a variety of human cancer cell lines, as well as to
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Tumor necrosis: factors and principles
Immunology Today, 1996Abstract Tumor necrosis is often caused by vasculature shutdown, and the exploitation of altered features of the vasculature within solid tumors may give rise to novel forms of therapy. A recent meeting ∗ ∗The symposium ‘Tumor Necrosis: Factors and Principles' was held at Ringberg, Germany, on 29 October–1 November 1995.
D, Männel +3 more
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Tumor necrosis factor and the therapeutic potential of anti-tumor necrosis factor antibodies
Critical Care Medicine, 1993To review the relationship of tumor necrosis factor (TNF) to clinical sepsis and the clinical potential of anti-TNF therapy in decreasing morbidity and mortality rates due to sepsis.The international English language literature was reviewed, including animal studies and human clinical trials regarding TNF, anticytokine therapy, and sepsis.Studies which
J C, Wherry +2 more
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Tumor Necrosis Factor in Humans
New England Journal of Medicine, 1988When immune cells are stimulated in a variety of ways, they release soluble proteins called cytokines.
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The Pathophysiology of Tumor Necrosis Factors
Annual Review of Immunology, 1992Tumor necrosis factor (TNF) came to birth in a strange way. It made its entry into the world of biology and medicine when Lloyd Old discovered that the capacity to induce, in vivo and in vitro, the necrosis of some mouse tumors could be ascribed to a factor (rapidly identified as a protein) present in the blood after LPS injection ( 1 ) . Then, at what
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Tumor necrosis factor and immunopathology
Immunologic Research, 1991Piguet PF, Grau GE, Vassalli P
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Are There More Tumor Necrosis Factors?
JNCI Journal of the National Cancer Institute, 1989openaire +2 more sources