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Tumor Necrosis Factor Alpha Signaling and Organogenesis [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
Kai You   +4 more
doaj   +4 more sources

The concentration of tumor necrosis factor alpha in periapical lesions [PDF]

open access: yesStomatološki glasnik Srbije, 2014
Introduction. The balance between proinflammatory and anti-inflammatory cytokines plays an important role in the pathogenesis of chronic periapical lesions.
Popović Jelena   +6 more
doaj   +4 more sources

Implication of Tumor Necrosis Factor - Alpha in Preeclampsia [PDF]

open access: yesApplied Medical Informatics, 2008
Introduction: Preeclampsia is an exacerbation of a generalized inflammatory response, physiologically present in the third trimester of pregnancy.Aim: The aim of the study consists in the evaluation of proinflammatory cytokine TNF-α in the context of ...
Dan MIHU   +4 more
doaj   +2 more sources

Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity

open access: yesMediators of Inflammation, 2014
Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
doaj   +2 more sources

Tumor necrosis factor alpha in sleep regulation

open access: yesSleep Medicine Reviews, 2018
This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep.
Rockstrom, Matthew D   +6 more
openaire   +5 more sources

Tumor necrosis factor-alpha in patients with alopecia areata

open access: yesIndian Journal of Dermatology, 2011
Background : Alopecia areata (AA) is a common form of localized, nonscarring hair loss. It is characterized by the loss of hair in patches, total loss of scalp hair (alopecia totalis, AT), or total loss of body hair (alopecia universalis, AU).
Emina Kasumagic-Halilovic   +2 more
doaj   +3 more sources

Targeting Tumor Necrosis Factor Alpha for Alzheimer’s Disease [PDF]

open access: yesCurrent Alzheimer Research, 2017
Alzheimer’s disease (AD) affects an estimated 44 million individuals worldwide, yet no therapeutic intervention is available to stop the progression of the dementia. Neuropathological hallmarks of AD are extracellular deposits of amyloid beta (Aβ) peptides assembled in plaques, intraneuronal accumulation of hyperphosphorylated tau protein forming ...
Decourt, Boris   +2 more
openaire   +3 more sources

Glaucomatous neurodegeneration: An eye on tumor necrosis factor-alpha

open access: yesIndian Journal of Ophthalmology, 2012
Glaucoma, a neurodegenerative disease, is currently being treated by modulation of one of its primary risk factors, the elevated intraocular pressure. Newer therapies that can provide direct neuroprotection to retinal ganglion cells are being extensively
Renu Agarwal, Puneet Agarwal
doaj   +3 more sources

Induction of tumor necrosis factor alpha gene expression by lipoprotein lipase.

open access: hybridJournal of Lipid Research, 1994
In view of the suppressive effect of tumor necrosis factor alpha (TNF alpha) on lipoprotein lipase (LPL) and of the potential proatherogenic effects of these two macrophage secretory products, we have tested the possibility that LPL could modulate the ...
G Renier   +3 more
doaj   +2 more sources

Comparative Analysis of TNF-alpha, TNF-R1, and TNF-R2 in Patients with Low-impact Fractures Due to Osteoporosis [PDF]

open access: yesRevista Brasileira de Ortopedia, 2023
Objective To analyze the serum levels of TNF-alpha and its TNF-R1 and TNF-R2 receptors in the blood of patients with low-impact fractures due to osteoporosis, comparing between genders and with healthy patients. Methods The present study was conducted
Abel Oliveira Marques Teixeira   +5 more
doaj   +1 more source

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