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Tumor Necrosis Factor Alpha Signaling and Organogenesis [PDF]
Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
Kai You+4 more
doaj +3 more sources
The concentration of tumor necrosis factor alpha in periapical lesions [PDF]
Introduction. The balance between proinflammatory and anti-inflammatory cytokines plays an important role in the pathogenesis of chronic periapical lesions.
Popović Jelena+6 more
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Targeting Tumor Necrosis Factor Alpha for Alzheimer's Disease. [PDF]
Alzheimer’s disease (AD) affects an estimated 44 million individuals worldwide, yet no therapeutic intervention is available to stop the progression of the dementia. Neuropathological hallmarks of AD are extracellular deposits of amyloid beta (Aβ) peptides assembled in plaques, intraneuronal accumulation of hyperphosphorylated tau protein forming ...
Boris Decourt, D. Lahiri, M. Sabbagh
semanticscholar +4 more sources
Implication of Tumor Necrosis Factor - Alpha in Preeclampsia [PDF]
Introduction: Preeclampsia is an exacerbation of a generalized inflammatory response, physiologically present in the third trimester of pregnancy.Aim: The aim of the study consists in the evaluation of proinflammatory cytokine TNF-α in the context of ...
Dan MIHU+4 more
doaj +2 more sources
Tumor necrosis factor-alpha inhibitor treatment for sarcoidosis
José Luis Callejas-Rubio, Lourdes López-Pérez, Norberto Ortego-CentenoUnit of Autoimmune Systemic Diseases, Hospital Clinico San Cecilio, Granada, SpainAbstract: Sarcoidosis is a chronic multisystem disease of unknown ...
José Luis Callejas-Rubio+2 more
doaj +6 more sources
Tumor necrosis factor alpha in sleep regulation.
This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep.
M. Rockstrom+6 more
semanticscholar +6 more sources
Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity
Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
doaj +2 more sources
Glaucomatous neurodegeneration: An eye on tumor necrosis factor-alpha
Glaucoma, a neurodegenerative disease, is currently being treated by modulation of one of its primary risk factors, the elevated intraocular pressure. Newer therapies that can provide direct neuroprotection to retinal ganglion cells are being extensively
Renu Agarwal, Puneet Agarwal
doaj +4 more sources
Tumor necrosis factor-alpha in patients with alopecia areata
Background : Alopecia areata (AA) is a common form of localized, nonscarring hair loss. It is characterized by the loss of hair in patches, total loss of scalp hair (alopecia totalis, AT), or total loss of body hair (alopecia universalis, AU).
Emina Kasumagic-Halilovic+2 more
doaj +4 more sources
Laurelee Osborn, S. Kunkel, G. Nabel
semanticscholar +2 more sources