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Tumor Necrosis Factor Alpha Signaling and Organogenesis [PDF]
Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
Kai You +4 more
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The concentration of tumor necrosis factor alpha in periapical lesions [PDF]
Introduction. The balance between proinflammatory and anti-inflammatory cytokines plays an important role in the pathogenesis of chronic periapical lesions.
Popović Jelena +6 more
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Implication of Tumor Necrosis Factor - Alpha in Preeclampsia [PDF]
Introduction: Preeclampsia is an exacerbation of a generalized inflammatory response, physiologically present in the third trimester of pregnancy.Aim: The aim of the study consists in the evaluation of proinflammatory cytokine TNF-α in the context of ...
Dan MIHU +4 more
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Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity
Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
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Tumor necrosis factor alpha in sleep regulation
This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep.
Rockstrom, Matthew D +6 more
openaire +5 more sources
Tumor necrosis factor-alpha in patients with alopecia areata
Background : Alopecia areata (AA) is a common form of localized, nonscarring hair loss. It is characterized by the loss of hair in patches, total loss of scalp hair (alopecia totalis, AT), or total loss of body hair (alopecia universalis, AU).
Emina Kasumagic-Halilovic +2 more
doaj +3 more sources
Targeting Tumor Necrosis Factor Alpha for Alzheimer’s Disease [PDF]
Alzheimer’s disease (AD) affects an estimated 44 million individuals worldwide, yet no therapeutic intervention is available to stop the progression of the dementia. Neuropathological hallmarks of AD are extracellular deposits of amyloid beta (Aβ) peptides assembled in plaques, intraneuronal accumulation of hyperphosphorylated tau protein forming ...
Decourt, Boris +2 more
openaire +3 more sources
Glaucomatous neurodegeneration: An eye on tumor necrosis factor-alpha
Glaucoma, a neurodegenerative disease, is currently being treated by modulation of one of its primary risk factors, the elevated intraocular pressure. Newer therapies that can provide direct neuroprotection to retinal ganglion cells are being extensively
Renu Agarwal, Puneet Agarwal
doaj +3 more sources
Induction of tumor necrosis factor alpha gene expression by lipoprotein lipase.
In view of the suppressive effect of tumor necrosis factor alpha (TNF alpha) on lipoprotein lipase (LPL) and of the potential proatherogenic effects of these two macrophage secretory products, we have tested the possibility that LPL could modulate the ...
G Renier +3 more
doaj +2 more sources
Comparative Analysis of TNF-alpha, TNF-R1, and TNF-R2 in Patients with Low-impact Fractures Due to Osteoporosis [PDF]
Objective To analyze the serum levels of TNF-alpha and its TNF-R1 and TNF-R2 receptors in the blood of patients with low-impact fractures due to osteoporosis, comparing between genders and with healthy patients. Methods The present study was conducted
Abel Oliveira Marques Teixeira +5 more
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