Macrophage tumor necrosis factor-alpha release is induced by contact with some tumors. [PDF]
, 1990 Jeffrey D. Hasday +2 more
openalex +1 more source
Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion
Advanced Science, EarlyView.Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen +9 more
wiley +1 more source
Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population
Advanced Science, EarlyView.This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen +16 more
wiley +1 more source
Tumor necrosis factor-alpha enhances platelet activation via cathepsin G released from neutrophils. [PDF]
, 1991 Patricia Renesto, Michel Chignard
openalex +1 more source
Advanced Science, EarlyView.This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao +4 more
wiley +1 more source
Differential action of cycloheximide and activation stimuli on transcription of tumor necrosis factor-alpha, IL-1 beta, IL-8, and P53 genes in human monocytes. [PDF]
, 1993 Oleg Osipovich +6 more
openalex +1 more source
Advanced Science, EarlyView.Hypoxic and low‐glucose conditions in tumor tissues trigger colorectal tumor cell pyroptosis via sequential activation of the Caspase‐1/Caspase‐6/GSDMC axis. High mobility group box 1 (HMGB1), released from GSDMC‐mediated pyroptotic tumor cells, upregulates CXCL2 expression in adjacent tumor cells, thereby recruiting myeloid‐derived suppressor cells ...
Hanchao Gao +11 more
wiley +1 more source
Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor- alpha secretion [PDF]
, 1994 Naoki Oyaizu +5 more
openalex +1 more source
Advanced Science, EarlyView.This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran +7 more
wiley +1 more source
Modulation of receptors and cytotoxic response of tumor necrosis factor-alpha by various lectins.
, 1986 B B Aggarwal +2 more
openalex +1 more source