Results 11 to 20 of about 230,065 (144)

Evaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2015
Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are ...
Roshanak Abutorabi   +4 more
doaj   +1 more source

The assessment of TNF-α interaction with oligopeptide Trp-Asn-Trp-Val in vitro [PDF]

open access: yesВестник Витебского государственного медицинского университета, 2022
The hyperproduction of TNF-α in the human body is a pathogenetic factor of many diseases development. The widespread clinical use of anticytokine drugs based on antibodies has a number of limitations.
T.V. Ryabtseva   +2 more
doaj   +1 more source

The concentration of tumor necrosis factor alpha in periapical lesions [PDF]

open access: yesStomatološki glasnik Srbije, 2014
Introduction. The balance between proinflammatory and anti-inflammatory cytokines plays an important role in the pathogenesis of chronic periapical lesions.
Popović Jelena   +6 more
doaj   +1 more source

Influence of ?S-globin haplotypes and hydroxyurea on tumor necrosis factor-alpha levels in sickle cell anemia

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2014
Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino   +5 more
doaj   +1 more source

Asporin expression is highly regulated in human chondrocytes [PDF]

open access: yesMolecular Medicine, Feinstein Institute for Medical Research, 2010, 17 (7-8), pp.816-23, 2015
A significant association between a polymorphism in the D repeat of the gene encoding asporin and osteoarthritis, the most frequent of articular diseases, has been recently reported. The goal of the present study was to investigate the expression of this new class I small leucine-rich proteoglycan (SLRP) in human articular chondrocytes.
arxiv   +1 more source

Understanding the immunopathogenic bases and the clinical approach of the periodic syndrome associated with the tumor necrosis receptor, TRAPS

open access: yesIatreia, 2018
Tumor necrosis factor receptor periodic syndrome (TRAPS) is characterized by episodes of fever of more than 10 days of duration, migratory myalgias, pseudocellulitis, abdominal pain and bipalpebral edema.
Moreno Zuluaga, Catalina   +1 more
doaj   +1 more source

Bifurcation analysis of a free boundary model of vascular tumor growth with a necrotic core and chemotaxis [PDF]

open access: yesarXiv, 2022
A considerable number of research works has been devoted to the study of tumor models. Several biophysical factors, such as cell proliferation, apoptosis, chemotaxis, angiogenesis and necrosis, have been discovered to have an impact on the complicated biological system of tumors.
arxiv  

Application of a stochastic modeling to evaluate tuberculosis onset in patients treated with tumor necrosis factor inhibitors [PDF]

open access: yesAgliari E, Asti L, Barra A, Scrivo R, Valesini G, Wallis RS. PLoS ONE 8(1): e55017 (2013), 2012
In this manuscript we apply stochastic modeling to investigate the risk of reactivation of latent mycobacterial infections in patients undergoing treatment with tumor necrosis factor inhibitors. First, we review the perspective proposed by one of the authors in a previous work and which consists in predicting the occurrence of reactivation of latent ...
arxiv   +1 more source

Implication of Tumor Necrosis Factor - Alpha in Preeclampsia [PDF]

open access: yesApplied Medical Informatics, 2008
Introduction: Preeclampsia is an exacerbation of a generalized inflammatory response, physiologically present in the third trimester of pregnancy.Aim: The aim of the study consists in the evaluation of proinflammatory cytokine TNF-α in the context of ...
Dan MIHU   +4 more
doaj  

Integrated probability of coronary heart disease subject to the -308 tumor necrosis factor-alpha SNP: a Bayesian meta-analysis [PDF]

open access: yes, 2015
We present a meta-analysis of independent studies on the potential implication in the occurrence of coronary heart disease (CHD) of the single-nucleotide polymorphism (SNP) at the -308 position of the tumor necrosis factor alpha (TNF-alpha) gene. We use Bayesian analysis to integrate independent data sets and to infer statistically robust measurements ...
arxiv   +1 more source

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