Results 61 to 70 of about 659,836 (375)

Hubungan antara Tumor Necrosis Factor Alpha dengan Demam Berdarah Dengue

Sari Pediatri, 2016
Latar belakang. Sampai saat ini patogenesis demam berdarah dengue (DBD) belum dipahami secara sempurna. Pada kasus DBD didapatkan adanya peningkatan kadar TNF-α, sitokin yang poten dalam meningkatkan permeabilitas pembuluh darah.
Felix Candra Sutanto, Max F.J. Mantik, Vivekenanda Pateda   +2 more
doaj   +1 more source

Comparison of Machine Learning Classifiers to Predict Patient Survival and Genetics of GBM: Towards a Standardized Model for Clinical Implementation [PDF]

arXiv, 2021
Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning classifiers, with different optimization parameters, to predict overall survival (OS), isocitrate dehydrogenase (IDH ...
arxiv  

Sinusitis in patients on tumor necrosis factor alpha inhibitors [PDF]

International Forum of Allergy & Rhinology, 2016
BackgroundTumor necrosis factor alpha (TNF‐α) inhibitors have revolutionized treatment of many inflammatory diseases. Sinusitis after initiation of TNF‐α inhibitors has been observed, but has not been well described in the literature. We aim to characterize the clinical features of sinusitis in patients on anti‐TNF‐α therapy.MethodsThis is a ...
Adam Honeybrook, Nikita Chapurin, Anjeni Keswani, Cynthia S. Wang, David W. Jang   +4 more
openaire   +3 more sources

Adults with major depression who are suicidal and those who aren't have different cytokines and lipid profiles. [PDF]

, 2022
OBJECTIVES: We tested whether Tumor necrosis factor-alpha, Interlukin-1β, and lipid profile might be associated with suicide attempts in adult patients with major depression.
arlene gitomer
core   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Targeted Cancer Therapy with Tumor Necrosis Factor-Alpha [PDF]

Biochemistry Insights, 2008
Tumor necrosis factor-alpha (TNF-α), a member of the TNF superfamily, was the first cytokine to be evaluated for cancer biotherapy. However, the clinical use of TNF-α is severely limited by its toxicity. Currently, TNF-α is administered only through locoregional drug delivery systems such as isolated limb perfusion and isolated hepatic perfusion.
Weibo Cai, Hao Hong, Zachary Kerner, Jiangtao Sun   +3 more
openaire   +3 more sources

Systemic inflammatory profile and response to anti-tumor necrosis factor therapy in chronic obstructive pulmonary disease [PDF]

, 2012
Background Chronic obstructive pulmonary disease (COPD) is characterized by progressive worsening of airflow limitation associated with abnormally inflamed airways in older smokers.
Baribaud, Frédéric, Barnathan, Elliot S, Loza, Matthew J, Rennard, Stephen I, Watt, Rosemary   +4 more
core   +3 more sources

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, Volume 19, Issue 5, Page 1347-1370, May 2025.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Psoriasiform Sarcoidosis Presenting in Pregnancy and Treatment Considerations [PDF]

, 2018
Cutaneous sarcoidosis is a common presentation for patients with sarcoidosis. Rarely, patients can present with psoriasiform lesions mimicking chronic plaque psoriasis. Here, we present a case of psoriasiform sarcoidosis in a pregnant patient.
Albornoz, Christian A., Keller, Matthew, Wang, Jordan   +2 more
core   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source