Results 61 to 70 of about 497,020 (311)

Serum tumor necrosis factor alpha and C-reactive protein increase in breast cancer patients [PDF]

Al Ameen Journal of Medical Sciences, 2018
Background: Breast cancer is now the second most commonly cancer diagnosed in women and remains the leading cause of cancer death among females in less developed countries.
Johnkennedy Nnodim, Orji Somtochukwu M, Ihionu Chukwudozie A   +2 more
doaj  

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Induction of tumor necrosis factor alpha gene expression by lipoprotein lipase.

Journal of Lipid Research, 1994
In view of the suppressive effect of tumor necrosis factor alpha (TNF alpha) on lipoprotein lipase (LPL) and of the potential proatherogenic effects of these two macrophage secretory products, we have tested the possibility that LPL could modulate the ...
G Renier, E Skamene, J B DeSanctis, D Radzioch   +3 more
doaj   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Factor de necrosis tumoral alfa en pacientes con preeclampsia a término y pretérmino

Avances en Biomedicina, 2012
El objetivo de la investigación fue identificar y comparar las concentraciones de factor de necrosis tumoral alfa en pacientes con preeclampsia a término y pre-término. Se seleccionó un total de 50 pacientes.
Eduardo Reyna Villasmil, Jorly Mejia Montilla, Nadia Reyna Villasmil, Duly Torres Cepeda, Joel Santos Bolívar, Jhoan Aragón Charry   +5 more
doaj  

LEVELS OF TUMOR NECROSIS FACTOR ALPHA IN PATIENTS WITH ISCHEMIC STROKE

Медицинская иммунология, 2019
Ischemic stroke is the most common form of brain stroke. It is associated with functional changes of various blood and bone marrow cell populations, altered release of various cytokines, chemokines, etc.
I. A. Prilutskaya, Yu. Ya. Kryuk
doaj   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source

Nilai Prognostik Tumor Necrosis Factor Alpha Demam Berdarah Dengue pada Anak

Sari Pediatri, 2016
Latar belakang. Demam berdarah dengue (DBD) adalah penyakit yang disebabkan oleh virus dengue. Patogenesisnya sampai saat ini belum jelas. Sitokin diduga berperan dalam patogenesis DBD. Prognosis sulit diramalkan. Tujuan.
Idham Jaya Ganda
doaj   +1 more source

Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light

Journal of Experimental Medicine, 1990
Tumor necrosis factor alpha (TNF-alpha), in addition to being cytotoxic for certain tumor cells, has turned out as a multifunctional cytokine that is involved in the regulation of immunity and inflammation.
Andreas K6ck, Thomas Schwarz, R. Kirnbauer, A. Urbanski, Patricia Perry, J. Ansel, T. Luger   +6 more
semanticscholar   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source