Results 21 to 30 of about 5,001,621 (350)

Mapping the immune environment in clear cell renal carcinoma by single-cell genomics

Communications Biology, 2021
Clear cell renal cell carcinoma (ccRCC) is one of the most immunologically distinct tumor types due to high response rate to immunotherapies, despite low tumor mutational burden.
Nicholas C. Borcherding, Ajaykumar Vishwakarma, Andrew P. Voigt, A. Bellizzi, J. Kaplan, K. Nepple, A. Salem, Russell W. Jenkins, Y. Zakharia, Weizhou Zhang   +9 more
semanticscholar   +1 more source

Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling [PDF]

, 2014
BACKGROUND: Proteomics-based approaches for biomarker discovery are promising strategies used in cancer research. We present state-of-art label-free quantitative proteomics method to assess proteome of renal cell carcinoma (RCC) compared with noncancer ...
J T-J Huang, Bray, S E, Fleming, S., Lamont, D J, D J Lamont, Zakikhani, P, P Zakikhani, M A V Mudaliar, Atrih, A, S Fleming, Zakikhani, P., Lamont, D. J., Barton, G.; id_orcid, G Nabi, G Barton, A Atrih, Bray, S. E., Barton, G, Huang, J. T.-J.; id_orcid, Mudaliar, M. A. V., Atrih, A., Fleming, S, Nabi, G, Nabi, G., Huang, J T-J, S E Bray, Mudaliar, M A V   +26 more
core   +1 more source

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery [PDF]

, 2014
Background:Wider clinical applications of 9p status in clear cell renal cell carcinoma (ccRCC) are limited owing to the lack of validation and consensus for interphase fluorescent in situ hybridisation (I-FISH) scoring technique.
Fleming, S., P Rauchhaus, J Fitzpatrick, Fitzpatrick, J., N Pratt, S Fleming, J Bondad, J Cunningham, El-Mokadem, I., Cunningham, J., Bondad, J., Nabi, G., Rauchhaus, P., G Nabi, Pratt, N., I El-Mokadem   +15 more
core   +1 more source

Renal Tumors in the Rabbit [PDF]

The American Journal of the Medical Sciences, 1917
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Bell,, Henrici,
openaire   +2 more sources

Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma [PDF]

, 2010
Background: The enhancer of zeste homolog 2 (EZH2) gene exerts oncogene-like activities and its (over)expression has been linked to several human malignancies. Here, we studied a possible association between EZH2 expression and prognosis in patients with
Johannes Hüsing, Wagener, Nina, Hüsing Johannes, Karin Hoppe-Seyler, Hoppe-Seyler Felix, Peter Schirmacher, Hoppe-Seyler, Karin, Pfitzenmaier, Jesco, Macher-Göppinger, Stephan, Jesco Pfitzenmaier, Hohenfellner, Markus, Hüsing, Johannes, Haferkamp, Axel, Haferkamp Axel, Stephan Macher-Goeppinger, Maria Pritsch, Wagener Nina, Pritsch Maria, Axel Haferkamp, Schirmacher Peter, Nina Wagener, Hoppe-Seyler Karin, Hohenfellner Markus, Felix Hoppe-Seyler, Hoppe-Seyler, Felix, Pfitzenmaier Jesco, Macher-Goeppinger Stephan, Markus Hohenfellner, Pritsch, Maria, Schirmacher, Peter   +29 more
core   +1 more source

Sporadic angiomyolipoma of the kidney with associated renal vein tumor thrombus

Current Problems in Cancer: Case Reports, 2020
Introduction: A renal angiomyolipoma (AML) is a benign kidney tumor that is most often discovered incidentally on imaging. It is generally asymptomatic, benign, and lacks the potential for invasion or metastasis.
Tanner J. Wright, Paula Jenkins Colon, Funda Vakar-Lopez, Ramasamy Bakthavatsalam, Sarah P. Psutka   +4 more
doaj   +1 more source

Significance of chromosome 9p status in renal cell carcinoma:a systematic review and quality of the reported studies [PDF]

, 2014
Defining the prognosis of renal cell carcinoma (RCC) using genetic tests is an evolving area. The prognostic significance of 9p status in RCC, although described in the literature, remains underutilised in clinical practice. The study explored the causes
El-Mokadem, Ismail, Fitzpatrick, John, Cunningham, J., Nabi, Ghulam, Pratt, Norman, Fleming, Stewart, Rai, Bhavan   +6 more
core   +1 more source

Needle tract seeding in renal tumor biopsies: experience from a single institution

Diagnostic Pathology, 2021
Background Percutaneous needle biopsy of renal masses has been increasingly utilized to aid the diagnosis and guide management. It is generally considered as a safe procedure.
Yan Zhou, Paari Murugan, Faqian Li, Lihong Bu   +3 more
doaj   +1 more source

Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

Genome Biology, 2016
Tumor-infiltrating immune cells have been linked to prognosis and response to immunotherapy; however, the levels of distinct immune cell subsets and the signals that draw them into a tumor, such as the expression of antigen presenting machinery genes ...
Y. Şenbabaoğlu, Ron S. Gejman, A. Winer, Ming Liu, E. V. Van Allen, G. de Velasco, Diana Miao, I. Ostrovnaya, E. Drill, Augustin Luna, Nils Weinhold, William Lee, B. Manley, D. Khalil, S. Kaffenberger, Yingbei Chen, Ludmila V. Danilova, M. Voss, J. Coleman, P. Russo, V. Reuter, T. Chan, E. Cheng, D. Scheinberg, Ming O. Li, T. Choueiri, J. Hsieh, C. Sander, A. Hakimi   +28 more
semanticscholar   +1 more source

Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

Nature Medicine, 2020
PD-1 blockade has transformed the management of advanced clear cell renal cell carcinoma (ccRCC), but the drivers and resistors of the PD-1 response remain incompletely elucidated.
D. Braun, Yue Hou, Z. Bakouny, M. Ficial, Miriam Sant’ Angelo, J. Forman, P. Ross-Macdonald, Ashton C. Berger, O. Jegede, L. Elagina, J. Steinharter, Maxine Sun, M. Wind-Rotolo, Jean-Christophe Pignon, A. Cherniack, Lee T. Lichtenstein, D. Neuberg, P. Catalano, G. Freeman, A. Sharpe, D. McDermott, E. V. Van Allen, S. Signoretti, Catherine J. Wu, S. Shukla, T. Choueiri   +25 more
semanticscholar   +1 more source