Results 31 to 40 of about 5,001,621 (350)

Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells [PDF]

, 2009
Background Treatment options for metastatic renal cell carcinoma (RCC) are limited due to resistance to chemo- and radiotherapy. The development of small-molecule multikinase inhibitors have now opened novel treatment options.
Natsheh, Iyad Y. M., Eva Juengel, Mickuckyte, Ausra, Hudak, Lukasz, Jones, Jon, Roman A Blaheta, Lukasz Hudak, Jüngel, Eva, Dietger Jonas, Blaheta, Roman A., Johanna Engler, Iyad Natsheh, Ausra Mickuckyte, Jonas, Dietger, Jon Jones, Engler, Johanna   +15 more
core   +1 more source

Tumor renal

Medisur, 2016
Yarisdey Corrales Hernández, Noelia Castro Ladrón de Guevara   +1 more
doaj   +3 more sources

Renal neuroendocrine tumors

Indian Journal of Urology, 2009
Neuroendocrine tumors (NETs) are uncommon tumors that exhibit a wide range of neuroendocrine differentiation and biological behavior. Primary NETs of the kidney, including carcinoid tumor, small cell carcinoma (SCC), and large cell neuroendocrine carcinoma (LCNEC) are exceedingly rare.The clinicopathologic features of renal NETs diagnosed at a single ...
Brian R Lane, George Jour, Ming Zhou
openaire   +3 more sources

Role of protein kinase C in renal vasoconstriction caused by angiotensin II [PDF]

, 1990
In this study we have examined the subcellar pathways along which angiotensin II (ANG II) causes renal vasoconstriction. Using the isolated perfused rat kidney model, we found that renal vasoconstriction produced by ANG II (100 pM) was not altered by the
Kurtz, Armin, Scholz, H., A. Kurtz, H. Scholz   +3 more
core   +1 more source

Tumor-Infiltrating and Peripheral Blood T-cell Immunophenotypes Predict Early Relapse in Localized Clear Cell Renal Cell Carcinoma

Clinical Cancer Research, 2017
Purpose: The efficacy of PD-1 checkpoint blockade as adjuvant therapy in localized clear cell renal cell carcinoma (ccRCC) is currently unknown. The identification of tumor microenvironment (TME) prognostic biomarkers in this setting may help define ...
Nicolas A. Giraldo, E. Becht, Y. Vano, F. Petitprez, L. Lacroix, P. Validire, R. Sanchez-Salas, A. Ingels, S. Oudard, Audrey Moatti, Bénédicte Buttard, Sarah Bourass, C. Germain, X. Cathelineau, W. Fridman, C. Sautès-Fridman   +15 more
semanticscholar   +1 more source

Tumor renal en ectopia renal cruzada con fusión

, 2005
Resumen La ectopia renal cruzada es una anomalia renal congenita poco frecuente y en la mayoria de los casos se presenta con fusion de ambos rinones. Estos pacientes suelen permanecer asintomaticos hasta la 4a-5a decada y desarrollar entonces problemas ...
C. A. Tubet, J. I. D. V. Schaan, B. M. Garcia, J. A. P. Martín, J. G. Baños, R. Diego   +5 more
semanticscholar   +1 more source

An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors

Cancer Discovery, 2018
By leveraging tumorgraft (PDX) RNA-Seq data, we developed an empirical approach, DisHet, to dissect the tumor microenvironment (eTME). We found that 65% of previously defined immune signature genes are not abundantly expressed in Renal Cell Carcinoma ...
Tao Wang, Rong Lu, P. Kapur, B. Jaiswal, R. Hannan, Ze Zhang, I. Pedrosa, J. Luke, He Zhang, Leonard D. Goldstein, Qurratulain Yousuf, Yi-feng Gu, Tiffani McKenzie, Allison Joyce, M. S. Kim, Xinlei Wang, Danni Luo, Oreoluwa Onabolu, C. Stevens, Zhiqun Xie, Mingyi Chen, A. Filatenkov, J. Torrealba, Xin Luo, Wenbin Guo, Jingxuan He, Eric W. Stawiski, Z. Modrusan, S. Durinck, S. Seshagiri, J. Brugarolas   +30 more
semanticscholar   +1 more source

Succinate dehydrogenase (SDH)-deficient renal carcinoma:a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients [PDF]

, 2014
Succinate dehydrogenase (SDH)-deficient renal carcinoma has been accepted as a provisional entity in the 2013 International Society of Urological Pathology Vancouver Classification.
Sedivcová, Monika, Yu, Darryl, Papathomas, Thomas, Niemeijer, Nicolasine D., Przybycin, Christopher, Nicoll, Katherine D, Paik, Julie, Miettinen, Markku, Yong, Jim L., Kedziora, Andrew, Andresen, Per Arne, Hes, Ondrej, Toon, Christopher W., Robinson, Bruce G, Corssmit, Eleonora P M, Michal, Michal, Chou, Angela, Hills, Kirsten, Nicoll, Katherine D., Clarkson, Adele, Clifton-bligh, Roderick J., Yong, Jim L, Maclean, Fiona, Yilmaz, Asli, Vlatkovic, Ljiljana, Niemeijer, Nicolasine D, Hartmann, Arndt, Sibony, Mathilde, Agaimy, Abbas, McKenney, Jesse K, Robinson, Bruce G., Van Leenders, Geert J.l.h., Chow, Chung W., Sioson, Loretta, Mckenney, Jesse K., Corssmit, Eleonora P.m., Tan, Puay Hoon, van Leenders, Geert J L H, Yakirevich, Evgeny, Trpkov, Kiril, Benn, Diana E., Gill, Anthony J., Chow, Chung W, Watson, Nicole, Fleming, Stewart, Magi-Galluzzi, Cristina, Clifton-Bligh, Roderick J   +46 more
core   +1 more source

Measurement of Glomerular Filtration Rate Using Multiphasic Computed Tomography in Patients With Unilateral Renal Tumors: A Feasibility Study

Frontiers in Physiology, 2019
ObjectivesThis study was to assess the feasibility of a modified multiphasic CT scan protocol combined with homemade software measurements of glomerular filtration rate (CT-GFR) and explore the effect of renal tumor volume on the calculation of CT-GFR ...
Tingting Wang, Tingting Wang, Yi Xu, Wangyan Liu, Pengfei Shao, Qiang Lv, Guanyu Yang, Lijun Tang   +7 more
doaj   +1 more source

Renal Ewing tumors

Annals of Oncology, 2013
Renal Ewing's sarcoma/primitive neuroectodermal tumor (ES/PNET) is extremely rare. Clinical symptoms are nonspecific presenting abdominal pain, palpable mass, and hematuria. Owing to advanced technology demonstrating the ES-specific EWS/ETS translocation, this differential diagnosis has become feasible.The German database of GPOH Ewing's sarcoma trials
S, Zöllner, U, Dirksen, H, Jürgens, A, Ranft   +3 more
openaire   +2 more sources