Results 41 to 50 of about 5,001,621 (350)

Current Management of Small Renal Masses, Including Patient Selection, Renal Tumor Biopsy, Active Surveillance, and Thermal Ablation.

Journal of Clinical Oncology, 2018
Renal cancer represents 2% to 3% of all cancers, and its incidence is rising. The increased use of ultrasonography and cross-sectional imaging has resulted in the clinical dilemma of incidentally detected small renal masses (SRMs).
Alejandro Sanchez, Adam S Feldman, A. Hakimi   +2 more
semanticscholar   +1 more source

Krüppel-like factor 8 (KLF8) is expressed in gliomas of different WHO grades and is essential for tumor cell proliferation. [PDF]

, 2012
Krüppel-like factor 8 (KLF8) has only recently been identified to be involved in tumor cell proliferation and invasion of several different tumor entities like renal cell carcinoma, hepatocellular carcinoma and breast cancer.
Schnell, Oliver, Kretzschmar Hans, Juerchott Kathrin, Eigenbrod, Sabina, Valerie Albrecht, Romagna, Alexander, Juerchott, Kathrin, Irene Jaehnert, Jörg-Christian Tonn, Eigenbrod Sabina, Hans Kretzschmar, Jaehnert, Irene, Sabina Eigenbrod (187226), Hans Kretzschmar (187242), Kretzschmar, Hans, Schichor Christian, Romagna, A., Albrecht, Valerie, Christian Schichor, Alexander Romagna, Schnell, O., Juerchott, K., Tonn, Jörg-Christian, Irene Jaehnert (187215), Albrecht, V., Schichor, C., Romagna Alexander, Valerie Albrecht (187218), Eigenbrod, S., Kathrin Juerchott (187233), Christian Schichor (187256), Schichor, Christian, Jörg-Christian Tonn (187250), Albrecht Valerie, Jaehnert, I., Kathrin Juerchott, Kretzschmar, H., Alexander Romagna (187206), Oliver Schnell (187202), Jaehnert Irene, Sabina Eigenbrod, Schnell Oliver, Tonn Jörg-Christian, Tonn, J., Oliver Schnell   +44 more
core   +1 more source

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

Nature Communications, 2017
The roles of long non-coding RNAs in cancer metabolism remain largely unexplored. Here we identify FILNC1 (FoxO-induced long non-coding RNA 1) as an energy stress-induced long non-coding RNA by FoxO transcription factors.
Zhen-Dong Xiao, Leng Han, Hyemin Lee, Zhuang Li, Yilei Zhang, Joelle A Baddour, Deepak Nagrath, C. Wood, J. Gu, Xifeng Wu, Han Liang, B. Gan   +11 more
semanticscholar   +1 more source

Avelumab plus axitinib versus sunitinib in advanced renal cell carcinoma: biomarker analysis of the phase 3 JAVELIN Renal 101 trial

Nature Medicine, 2020
We report on molecular analyses of baseline tumor samples from the phase 3 JAVELIN Renal 101 trial (n = 886; NCT02684006), which demonstrated significantly prolonged progression-free survival (PFS) with first-line avelumab + axitinib versus sunitinib in ...
R. Motzer, P. Robbins, T. Powles, L. Albiges, J. Haanen, J. Larkin, X. Mu, K. Ching, M. Uemura, S. Pal, B. Alekseev, G. Gravis, M. Campbell, K. Penkov, J. Lee, S. Hariharan, Xiao Wang, Weidong Zhang, Jing Wang, A. Chudnovsky, A. di Pietro, Amber C Donahue, T. Choueiri   +22 more
semanticscholar   +1 more source

Novel Imaging Methods for Renal Mass Characterization: A Collaborative Review

European Urology, 2022
Context: The incidental detection of localized renal masses has been rising steadily, but a significant proportion of these tumors are benign or indolent and, in most cases, do not require treatment.
E. Roussel, U. Capitanio, A. Kutikov, E. Oosterwijk, I. Pedrosa, S. Rowe, M. Gorin   +6 more
semanticscholar   +1 more source

Differential expression of prognostic proteomic markers in primary tumour, venous tumour thrombus and metastatic renal cell cancer tissue and correlation with patient outcome

, 2013
Renal cell carcinoma (RCC) is the most deadly of urological malignancies. Metastatic disease affects one third of patients at diagnosis with a further third developing metastatic disease after extirpative surgery.
Antony C P Riddick, Stewart Grant D., Laird Alexander, Alexander Laird, Grant D Stewart, Laird, Alexander, O'Mahony, Fiach C, Riddick, Antony C P, Riddick Antony C. P., O’Mahony Fiach C., Harrison David J., Fiach C O'Mahony, Jyoti Nanda, Harrison, David J, David J Harrison, O'Mahony, Fiach C., Riddick, Antony C. P., Nanda Jyoti, Nanda, Jyoti, Stewart, Grant D., O’Donnell Marie, O'Donnell, Marie, Stewart, Grant D, Marie O'Donnell, Harrison, David J.   +24 more
core   +2 more sources

Gene expression analysis in microdissected renal tissue - Current challenges and strategies [PDF]

, 2002
The architecture and compartmentalization of the kidney has stimulated the development of an array of microtechniques to study the functional differences between the distinct nephron segments. With the vast amounts of genomic sequence data now available,
Cohen, C. D., Kretzler, M.
core   +1 more source

Leiomiosarcoma renal con invasión intraperitoneal a través del mesocolon

Cirugía del Uruguay, 2020
Se presenta una observación de leiomiosarcoma de riñón izquierdo en una paciente de 41 años portadora de una neurofibroma tosis múltiple. El tumor, de gran tamaño, progresó a través del área vascular del mesocolon izquierdo sin infiltrarlo formando una ...
Raúl Praderi, J Pardie
doaj  

Cell surface engineering of renal cell carcinoma with glycosylphosphatidylinositol-anchored TIMP-1 blocks TGF-beta 1 activation and reduces regulatory ID gene expression [PDF]

, 2012
Tissue inhibitor of metalloproteinase 1 (TIMP-1) controls matrix metalloproteinase activity through 1:1 stoichiometric binding. Human TIMP-1 fused to a glycosylphosphatidylinositol (GPI) anchor (TIMP-1-GPI) shifts the activity of TIMP-1 from the ...
Notohamiprodjo, Susan, Jaeckel, Carsten, Djafarzadeh, Roghieh, Hofstetter, Monika, Nelson, Peter J., Rieth, Nicole   +5 more
core   +1 more source

Hemorragia retroperitoneal espontánea: presentación de tres casos clínicos

Revista Methodo
La hemorragia retroperitoneal espontánea (HRE) es una urgencia médica poco frecuente originada por el sangrado en la cavidad retroperitoneal, no resultante de traumatismos, procedimientos quirúrgicos o maniobras iatrogénicas, sino con trastornos de la ...
Rossi M, Vacirca A, Cabrera F, Gutierrez Magaldi I   +3 more
doaj   +1 more source