Results 51 to 60 of about 5,001,621 (350)

A proteogenomic analysis of clear cell renal cell carcinoma in a Chinese population

Nature Communications, 2022
Clear cell renal cell carcinoma (ccRCC) is a common and aggressive subtype of renal cancer. Here we conduct a comprehensive proteogenomic analysis of 232 tumor and adjacent non-tumor tissue pairs from Chinese ccRCC patients.
Y. Qu, Jinwen Feng, Xiaohui Wu, Lin Bai, Wenhao Xu, Lingli Zhu, Yang Liu, Fujiang Xu, Xuan Zhang, Guojian Yang, Jiacheng Lv, Xiu Chen, G. Shi, Hong-kai Wang, D. Cao, Hang Xiang, Lingling Li, S. Tan, H. Gan, Meng Sun, J. Qiu, Hailiang Zhang, Jianyuan Zhao, Dingwei Ye, C. Ding   +24 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Engaging the Immune Response to Normalize the Tumor Microenvironment [PDF]

, 2013
Solid tumors exist as heterogeneous populations comprised not only of malignant cells, but various other cell types, including cells that make up the vasculature, that can strongly influence tumorgenicity.
Sabins, Nina, Storkus, Walter
core  

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Teratoid Wilms Tumor: Report of Three Cases and Review of the Literature

Türk Patoloji Dergisi, 2019
Teratoid Wilms tumor is a rare variant of Wilms tumor composed predominantly of well-differentiated epithelial and/or mesenchymal heterologous elements. Like the classical Wilms tumor, this variant may also occur as a renal mass or may be found in extra ...
Doaa AL GHAMDI, Nasir BAKSHI, Mohammed AKHTAR   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Renal angiomyolipoma with inferior vena caval thrombus in a 32-year-old male

Indian Journal of Urology, 2009
Renal angiomyolipoma (AML) rarely presents with evidence of extension into the renal vein, inferior vena cava (IVC) or atrium. We report a case of a renal AML with a tumor thrombus to the IVC in a 32-year-old male.
Matthew W Christian, Timothy D Moon
doaj   +1 more source

Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma

Nature Medicine, 2018
We describe results from IMmotion150, a randomized phase 2 study of atezolizumab (anti-PD-L1) alone or combined with bevacizumab (anti-VEGF) versus sunitinib in 305 patients with treatment-naive metastatic renal cell carcinoma.
D. McDermott, M. Huseni, M. Atkins, R. Motzer, B. Rini, B. Escudier, L. Fong, R. Joseph, S. Pal, J. Reeves, M. Sznol, J. Hainsworth, W. Rathmell, W. Stadler, Thomas E. Hutson, M. Gore, A. Ravaud, S. Bracarda, C. Suarez, R. Danielli, V. Gruenwald, T. Choueiri, D. Nickles, S. Jhunjhunwala, E. Piault-Louis, A. Thobhani, J. Qiu, Daniel S. Chen, P. Hegde, Christina Schiff, G. Fine, T. Powles   +31 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Radio-pathological review of a metastatic renal cell carcinoma within a meningioma: A case report of collision tumor

Radiology Case Reports, 2020
We report a case of a collision tumor, a meningioma complicated with metastasis from a primary renal cell carcinoma. A 75-year-old man, with known history of renal cell carcinoma, and 10-year history of stable meningioma developed neurological symptoms ...
Ayman Nada, MD, PhD, Ahmed Abdelrahman, MD, Christopher Cunningham, MD, Joseph Cousins, PhD, MD   +3 more
doaj   +1 more source