Results 61 to 70 of about 2,219,170 (264)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Renal cell carcinoma with a tumor thrombus in the ureter: a case report

BMC Urology, 2011
Background Renal cell carcinoma (RCCs) is the most common malignancy of the kidney. When RCC progresses, it is known to form tumor thrombus in the renal vein and/or inferior vena cava.
Takeda Katsuji, Manabe Daisuke, Yamasaki Tomoya, Wada Koichiro, Fujita Osamu, Nakamura Satoko   +5 more
doaj   +1 more source

An Independent Validation of 2010 Tumor-Node-Metastasis Classification for Renal Cell Carcinoma: A Multi-center Study by the Urooncology Association of Turkey Renal Cancer-Study Group [PDF]

, 2017
Objective: The American Joint Committee on Cancer tumor-node-metastasis (TNM) classification has been updated by the 7th edition in 2010. The objective of the study was to evaluate cancer-specific survival (CSS) in patients with renal cell carcinoma (RCC)
Ozen, Haluk, Dirim, Ayhan, Urooncology Association of Turkey Renal Cancer-Study Group, Cavit Can, Yildirim, Asif, Asıf Yıldırım, Can, Cavit, Haluk Özen, Çağatay Göğüs, Ozkan, Tayyar Alp, Akdogan, Bulent, Gogus, Cagatay, Tayyar Alp Özkan, Saadettin Eskiçorapçı, Turkeri, Levent, Eskicorapci, Sadettin, Renal, Urooncology Assoc Turkey, Özgür Yaycıoğlu, Tukeri, Levent, Levent Türkeri, Ayhan Dirim, Bülent Akdoğan, Yaycioglu, Ozgur, Eskicorapci, Saadettin, Urooncology Association of Turkey Renal Cancer Study Group   +24 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Thrombus-like Tumor of Renal Cell Carcinoma Mimicking Transitional Cell Carcinoma of Kidney: A Case Report

Urology Case Reports, 2017
Renal cell carcinoma (RCC) is the most common malignancy of the kidney. It is not commonly form tumor thrombus in the ureter or renal pelvis. A 29-year-old woman presented with asymptomatic gross hematuria. Contrast CT study revealed a tumor suspected to
Dyandra Parikesit, Chaidir A. Mochtar, Budiana Tanurahardja, Sahat Matondang, Rainy Umbas, Agus Rizal Hamid   +5 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Huge schwannoma arising from the renal sinus: A case report with imaging and literature review

Radiology Case Reports
Renal sinus schwannomas are extremely rare. In this study, we inform a case of a large schwannoma that was suspected to have originated in the renal sinus based on preoperative imaging. A male in his 40s was referred to our hospital due to the incidental
Takahiro Yamamoto, MD, PhD, Akiko Narita, MD, PhD, Toshinobu Saga, MD, Hiroaki Okada, MD, PhD, Nozomu Matsunaga, MD, Hisashi Kawai, MD, PhD, Taiki Masumori, MD, PhD, Keishi Kajikawa, MD, PhD, Taishi Takahara, MD, PhD, Kojiro Suzuki, MD, PhD   +9 more
doaj   +1 more source

Renal cell carcinoma treatment during pregnancy: Histopathological findings suggestive of rapid tumor growth

IJU Case Reports, 2019
Introduction Diagnosis of renal cell carcinoma during pregnancy is rare. We report a case of renal cell carcinoma during pregnancy with rapid growth. Case presentation A 39‐year‐old woman presented to our hospital for treatment of renal tumor at 22 weeks
Takehiro Ohyama, Masaki Shimbo, Fumiyasu Endo, Yoko Kyono, Fumi Akitani, Tokuhito Hayashi, Kenji Komatsu, Kazuhito Matsushita, Kosuke Suzuki, Kazunori Hattori   +9 more
doaj   +1 more source

Renal Tumors: Diagnostic and Prognostic Biomarkers.

, 2013
The International Society of Urological Pathology convened a consensus conference on renal cancer, preceded by an online survey, to address issues relating to the diagnosis and reporting of renal neoplasia.
Srigley J. R., Tan P. H., Merino M. J., Cheng L., The ISUP Renal Tumor Panel, Rioux Leclercq N., Grignon D. J., Reuter V. E., Egevad L., Moch H., Netto G., Shen S. S., Delahunt B., MONTIRONI, RODOLFO   +13 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source