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Ferritin drug carrier (FDC) for tumor targeting therapy.

Journal of Controlled Release, 2019
Ferritin is an iron storage protein that plays a key role in iron homeostasis and anti-oxidation of cells. Due to its unique architecture of 24 self-assembling subunits and hollow cavity capable of encapsulating drugs, and an outer surface that can be ...
Jiuyang He, Kelong Fan, Xiyun Yan
semanticscholar   +1 more source

Paclitaxel-loaded pH responsive hydrogel based on self-assembled peptides for tumor targeting.

Biomaterials Science, 2019
Intratumoral delivery of chemotherapeutic agents may permit the localization of drugs in tumors, decrease nonspecific targeting and increase efficacy.
Faisal Raza   +10 more
semanticscholar   +1 more source

Tumor Microenvironment Responsive Drug‐Dye‐Peptide Nanoassembly for Enhanced Tumor‐Targeting, Penetration, and Photo‐Chemo‐Immunotherapy

Advanced Functional Materials, 2019
Nanomedicine constructed by therapeutics has unique and irreplaceable advantages in biomedical applications, especially in drug delivery for cancer therapy.
Jinrong Peng   +8 more
semanticscholar   +1 more source

Tumor antigen targets and tumor immunotherapy

Frontiers in Bioscience, 2006
Tumor immunology and immunotherapy attempt to use the exquisite specificity and lytic capability of the immune system to treat malignant disease with a minimum of damage to normal tissue. Increasing knowledge of the identity of tumor antigens should point the way to effective therapeutic vaccines or more specific immunotherapeutic strategies.
openaire   +2 more sources

Tumor‐Targeted Catalytic Immunotherapy

Advanced Materials
AbstractCancer immunotherapy holds significant promise for improving cancer treatment efficacy; however, the low response rate remains a considerable challenge. To overcome this limitation, advanced catalytic materials offer potential in augmenting catalytic immunotherapy by modulating the immunosuppressive tumor microenvironment (TME) through precise ...
En‐Li Yang   +5 more
openaire   +2 more sources

Colloidal Systems for Tumor Targeting

Hybridoma, 1997
The potential and limitations of targeted delivery of anticancer agents with colloidal particulate carriers is the subject of this contribution. Because over the years liposomes have gained the most attention as carrier system in the category of colloidal carrier systems, this paper focuses on the utility of the liposomal system for tumor targeting. It
Storm, G., Crommelin, D.J.A.
openaire   +3 more sources

Tumor-Targeting Agents

2021
Monoclonal antibodies are specific molecules with a high affinity for the cell surface proteins. Long circulation time in blood makes them unsuitable for imaging as well as therapy. The process of protein engineering improves antibody’s pharmacokinetics retaining the property of affinity and specificity.
Dhritiman Chakraborty   +2 more
openaire   +1 more source

Combination Vascular Targeted and Tumor Targeted Radioimmunotherapy

Cancer Biotherapy and Radiopharmaceuticals, 1999
Rat MAb 201B, which binds to murine thrombomodulin, can deliver up to 50% of the injected dose of attached radioisotopes to the lung vascular endothelium. We have shown previously that intravenous injection of about 30 microCi of 213Bi-MAb 201B, which delivers about 15 Gy of alpha irradiation to the lung, is capable of eradicating small lung colonies ...
S J, Kennel   +5 more
openaire   +2 more sources

Vascular Tumor Targeting

The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2007
To overcome the hurdles of conventional tumor therapy, efforts have been directed to wards the development of anti-angiogenic agents, since the growth of solid tumors is dependent on their capacity to acquire a blood supply. More recently, it has become apparent that the targeted destruction of the established tumor vasculature or the delivery of ...
Dragan Grabulovski, Dario Neri
openaire   +3 more sources

Rationally designed peptide-conjugated gold/platinum nanosystem with active tumor-targeting for enhancing tumor photothermal-immunotherapy.

Journal of Controlled Release, 2019
Because of the tumor heterogeneity, poor therapeutic outcome is obtained while the conventional treatments, such as surgery, radiotherapy, or chemotherapy are utilized alone.
Qian Yang   +7 more
semanticscholar   +1 more source

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