Results 281 to 290 of about 2,657,421 (309)
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There will be blood: targeting tumor vasculature
Blood, 2009Extradomain B of fibronectin (ED-B FN) is expressed in the vasculature of hematopoietic malignancies and appears to be an effective target for monoclonal antibody–based therapies.
Nathan, Fowler, Anas, Younes
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Advances in Tumor Targeted Liposomes
Current Molecular Medicine, 2018Cancer remains a deadly disease for effective treatment. Although anomalous tumor microenvironment is now widely exploited for targeted chemotherapy, safe and efficacious drug delivery to tumor cells is not still warranted. Liposomes are promising biodegradable and biocompatible nanocarriers having potential amenability for surface and internal ...
A, Jain, , Jain
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Targeting Immunotherapy to the Tumor Microenvironment
Journal of Cellular Biochemistry, 2017ABSTRACTTargeting drugs to the tumor microenvironment has long been appreciated as a means of increasing local concentrations and decreasing systemic toxicities. How drug targeting might apply to immune‐based therapies is less clear. In this review, we explain the immunology of cancer, with a focus on the principles of in situ vaccination.
Michael Dougan, Stephanie K. Dougan
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Targeting NKG2D in tumor surveillance
Expert Opinion on Therapeutic Targets, 2012NKG2D (natural killer group 2, member D) is expressed on the surface of all mouse and human NK cells, and subpopulation of T cells. Stimulation of NK cells through NKG2D triggers cell-mediated cytotoxicity and induces the production of cytokines. NKG2D binds to family of unique ligands with structurally similar to MHC class I, however, NKG2D ligands ...
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Targets of Protective Tumor Immunity
Annals of the New York Academy of Sciences, 2009The identification of antigens associated with tumor destruction is a major goal of cancer immunology. Several genetic and biochemical techniques have revealed a broad range of gene products that elicit immune recognition in cancer patients, but the biologic importance of these responses in most cases is poorly understood. While some targets are linked
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Brain and other central nervous system tumor statistics, 2021
Ca-A Cancer Journal for Clinicians, 2021Jill Barnholtz-Sloan, Carol Kruchko
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Recent Advances in Tumor Targeting via EPR Effect for Cancer Treatment
Journal of Personalized Medicine, 2021Nina Filipczak +2 more
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