Results 71 to 80 of about 9,826,714 (353)

Enhancement of doxorubicin anti-cancer activity by vascular targeting using IsoDGR/cytokine-coated nanogold

Journal of Nanobiotechnology, 2021
Background Gold nanospheres tagged with peptides containing isoDGR (isoAsp-Gly-Arg), an αvβ3 integrin binding motif, represent efficient carriers for delivering pro-inflammatory cytokines to the tumor vasculature.
Angelo Corti, Angelina Sacchi, Anna Maria Gasparri, Matteo Monieri, Giulia Anderluzzi, Barbara Colombo, Alessandro Gori, Anna Mondino, Flavio Curnis   +8 more
doaj   +1 more source

Immunogenicity of targeted lentivectors [PDF]

, 2014
To increase the safety and possibly efficacy of HIV-1 derived lentivectors (LVs) as an anti-cancer vaccine, we recently developed the Nanobody (Nb) display technology to target LVs to antigen presenting cells (APCs).
Adotévi, Bennett, Bevan, Bhardwaj, Bhardwaj, Bhardwaj, Blander, Bonehill, Bonehill, Breckpot, Breckpot, Breckpot, Charleston, Chuah, Collins, Collins, Collins, Collins, Cosset, Diebold, Donckier, Eggermont, Enk, Figdor, Gajewski, Garcia, Groettrup, Inaba, Kast, Lahoutte, Lévy, McCullough, Medzhitov, Melief, Mellman, Mortha, Moser, Moser, Munn, Naldini, Neyns, Noguiez-Hellin, Nussenzweig, Palena, Raes, Reis e Sousa, Reiser, Reiser, Richardson, Romani, Roncarolo, Sakuma, Schroyens, Semesyuk, Song, Storm, Thielemans, Thielemans, Thielemans, Thielemans, Torretta, Turk, Van Kooyk, Wang, Wang, Yamaguchi, Yewdell, Yu   +67 more
core   +3 more sources

Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy

Theranostics, 2020
Rationale: Developing an effective nanoplatform to realize 'multi-in-one' is essential to broaden the therapeutic potential of combination therapy.
Qi Zhan, Kaikai Yi, Hongzhao Qi, Sidi Li, Xueping Li, Qixue Wang, Yunfei Wang, Chaoyong Liu, Ming-zhe Qiu, Xubo Yuan, Jin Zhao, Xin Hou, C. Kang   +12 more
semanticscholar   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Increasing linc00261 expression may predict well cancer prognosis, based on the meta-analysis

Discover Oncology
Background linc00261 was reported to be deregulated in many tumor groups and was significantly associated with cancer prognosis. This investigation seeks to conduct a meta-analysis to explore the link between linc00261 levels and cancer outcomes. Methods
Xinyue He, Shixu Fang, Chen Wu, Jintong Na, Liping Zhong, Xiyu Liu   +5 more
doaj   +1 more source

Aptamer-Functionalized Fluorescent Silica Nanoparticles for Highly Sensitive Detection of Leukemia Cells

Nanoscale Research Letters, 2016
A simple, highly sensitive method to detect leukemia cells has been developed based on aptamer-modified fluorescent silica nanoparticles (FSNPs). In this strategy, the amine-labeled Sgc8 aptamer was conjugated to carboxyl-modified FSNPs via amide ...
Juntao Tan, Nuo Yang, Zixi Hu, Jing Su, Jianhong Zhong, Yang Yang, Yating Yu, Jianmeng Zhu, Dabin Xue, Yingying Huang, Zongqiang Lai, Yong Huang, Xiaoling Lu, Yongxiang Zhao   +13 more
doaj   +1 more source

Recent Advances in Transition-Metal Based Nanomaterials for Noninvasive Oncology Thermal Ablation and Imaging Diagnosis

Frontiers in Chemistry, 2022
With the developments of nanobiotechnology and nanomedicine, non-invasive thermal ablation with fewer side effects than traditional tumor treatment methods has received extensive attention in tumor treatment.
Qiuxia Peng, Zhangbo Qian, Huali Gao, Kun Zhang, Kun Zhang   +4 more
doaj   +1 more source

Engaging the Immune Response to Normalize the Tumor Microenvironment [PDF]

, 2013
Solid tumors exist as heterogeneous populations comprised not only of malignant cells, but various other cell types, including cells that make up the vasculature, that can strongly influence tumorgenicity.
Sabins, Nina, Storkus, Walter
core  

Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma. [PDF]

, 2017
Patients with metastatic uveal melanoma usually die within 1 year of diagnosis, emphasizing an urgent need to develop new treatment strategies. The liver is the most common site of metastasis.
Aplin, Andrew E., Cheng, Hanyin, Chua, Vivian, Davies, Michael A., Kageyama, Ken, Liao, Connie, Purwin, Timothy J., Sato, Takami, Terai, Mizue   +8 more
core   +2 more sources

Targeting M2-like tumor-associated macrophages is a potential therapeutic approach to overcome antitumor drug resistance

npj Precision Oncology
Tumor drug resistance emerges from the interaction of two critical factors: tumor cellular heterogeneity and the immunosuppressive nature of the tumor microenvironment (TME). Tumor-associated macrophages (TAMs) constitute essential components of the TME.
Shujing Wang, Jingrui Wang, Zhiqiang Chen, Jiamin Luo, Wei Guo, Lingling Sun, Lizhu Lin   +6 more
semanticscholar   +1 more source