Results 41 to 50 of about 90,141 (272)

Testicular tumors in children

Sakarya Tıp Dergisi, 2013
Testicular tumors in children are rare. Teratomas and yolk sacs tumor are most testicular tumors in children. Masses of testicular tumors are often painless. These may be misdiagnosed as a hydrocel. Tumor markers and Ultrasound used in diagnosed.
Turan Yıldız
doaj   +1 more source

Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study [PDF]

, 2019
LCTs are more frequent than generally believed, are associated with male infertility, cryptorchidism and gynecomastia, and should be treated conservatively (in compliant patients) with active surveillance, which appears to be a safe alternative to ...
Cantisani, Vito, Fattorini, Giorgio, Franco, Giorgio, Gianfrilli, Daniele, Isidori, Andrea M, Lenzi, Andrea, Leonardo, Costantino, Pofi, Riccardo, Pozza, Carlotta, Sbardella, Emilia, Tarsitano, Maria Grazia, Tenuta, Marta, Testis, Unit   +12 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Intraperitoneal seeding of a testicular mixed germ cell tumor following spontaneous intraperitoneal mass rupture with associated anti-NMDA paraneoplastic encephalitis

Urology Case Reports, 2023
A 25-year-old male was admitted to the neurological intensive care unit for neurologic deterioration, likely caused by a paraneoplastic syndrome secondary to testicular malignancy.
Morgan B. Marshall, Kassandra Dindinger-Hill, Umang Swami, Stephanie Lyden, Alejandro Sanchez   +4 more
doaj   +1 more source

Feminization and severe pancytopenia caused by testicular neoplasia in a cryptorchid dog [PDF]

, 2016
In this case report, a paraneoplastic syndrome caused by testicular neoplasia in a ten-year-old cryptorchid dog is described. Feminization and pancytopenia were observed, resulting from the testicular neoplastic production of estrogens.
Hebbelinck, Lien, Kitshoff, Adriaan, Paepe, Dominique, Vandenabeele, Sophie   +3 more
core  

Pan-urologic cancer genomic subtypes that transcend tissue of origin [PDF]

, 2017
Urologic cancers include cancers of the bladder, kidney, prostate, and testes, with common molecular features spanning different types. Here, we show that 1954 urologic cancers can be classified into nine major genomic subtypes, on the basis of ...
Bossé, Dominick, Chen, Fengju, Choueiri, Toni K, Creighton, Chad J, Gibbons, Don L, Hakimi, A. Ari, Hsieh, James J, Ittmann, Michael, Lalani, Aly-Khan A, Zhang, Yiqun   +9 more
core   +2 more sources

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Adult Pure Yolk Sac Tumor of The Testis. [PDF]

, 2012
Adult pure yolk sac tumor (YST) is extremely rare. In childhood pure yolk sac tumors are most frequently seen, whereas component of mixed germ cell testicular tumors observed in adults.
Jagtap, SV, Kshirsagar, AY, Nikumbh, DB
core  

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Quiste epidermoide testicular: Diagnóstico ecográfico preoperatorio y correlación radiopatológica

Revista Chilena de Radiología
La escasa incidencia del quiste epidermoide de testículo (1-2% de todos los tumores testiculares), hace de los hallazgos ecográficos la clave para realizar o al menos sugerir un diagnóstico prequirúrgico preciso, haciendo por tanto posible un tratamiento
Erick Santa Eulalia M, Pedro José Sánchez S, Ana Margot Jara D, Fernando Ernesto Trucco, Florin Olimpiu Lenghel   +4 more
doaj   +1 more source