Results 51 to 60 of about 90,141 (272)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Extra-gonadal germ cell tumour – what about the testis! [PDF]

, 2011
Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature
Christopher CKH,, Goh EH,, Johann FK,, Praveen S,, Razman J,, Zulkifli MZ,   +5 more
core  

Paraneoplastic cerebellar degeneration associated with lymphoepithelial carcinoma of the tonsil [PDF]

, 2013
Background: Paraneoplastic cerebellar degeneration (PCD) is a classical tumor-associated, immune-mediated disease typically associated with gynecological malignancies, small-cell lung-cancer or lymphoma.
Hartmann, Sylvia, Henke, Christian, Middendorp, Marcus, Rieger, Johannes, Steinmetz, Helmuth, Ziemann, Ulf   +5 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

TUMOR TESTICULAR CALCIFICANTE DE CELULAS GRANDES DE SERTOLI: COMUNICACION DE UN CASO

Revista Chilena de Radiología
Se presenta el caso de un paciente de 7 años con tumor testicular calcificante, de células grandes de Sertoli, multifocal y bilateral, diagnos-ticado con ultrasonografía, en el contexto de una historia familiar de Complejo de Carney, tratado con ...
Alonso Inzulza C, Yerka Krstulovic
doaj   +1 more source

Testis tumor associated to microlithiasis

Revista Paulista de Pediatria, 2013
OBJECTIVE: To discuss the relationship between testicular microlithiasis and testis tumors in children and to consider the chances of testis preserving surgery in specific cases.
Lisieux Eyer de Jesus, Felipe Maciel, Andrea Lima C. Monnerat, Marcia Antunes Fernandes, Samuel Dekermache   +4 more
doaj   +1 more source

Staghorn Calculus with Adenomatoid Tumor: A Case Report

Case Reports in Oncology, 2023
Testicular adenomatoid tumor is very rare. More understanding of the tumor and treatment is required for better outcomes. A 63-year-old man visited a urologist for staghorn calculus.
Emad Tashkandi
doaj   +1 more source

Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]

, 2016
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia, Lara, H. E., Recabarren, S. E., Roselli, C. E., Zubeldia Brenner, Lautaro   +4 more
core   +2 more sources

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Blood mir-331-3p is a potential diagnostic marker for giant panda (Ailuropoda melanoleuca) testicular tumor

BMC Veterinary Research
Background In recent years, several giant pandas have suffered from testicular tumor, which has seriously affected giant panda health. However, the pathogenesis of testicular tumor in giant panda is still unclear.
Yan Zhu, Zhi Huang, Caiwu Li, Chengyao Li, Ming Wei, Linhua Deng, Wenwen Deng, Xiao Zhou, Kai Wu, Bo Yang, Yuanyuan Qu, Qin Liu, Xuemei Chen, Desheng Li, Chengdong Wang   +14 more
doaj   +1 more source