Results 81 to 90 of about 1,289,245 (239)

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

A Case of a Rare Testicular Tumor With Synchronous Malignancy. [PDF]

IJU Case Rep
ABSTRACT Introduction Leydig cell tumors are an uncommon malignancy accounting for 1%–2% of all testicular tumors. Synchronous, non‐testicular malignancy is a rare finding. Case Presentation A 51‐year‐old male presented with left testicular pain, and a scrotal ultrasound revealed a testicular mass.
Hoyt L, Trimble OA, Zopp J, Heubach K, Stencel MG.   +4 more
europepmc   +2 more sources

Effects of FSH on testicular mRNA transcript levels in the hypogonadal mouse [PDF]

, 2009
Follicle stimulating hormone (FSH) acts through the Sertoli cell to ensure normal testicular development and function. To identify transcriptional mechanisms through which FSH acts in the testis we have treated gonadotrophin-deficient hypogonadal (hpg ...
Abel, M.H., Lee, S., Charlton, H.M., O'Shaughnessy, P.J., Baban, D.   +4 more
core   +1 more source

Primary BPH Stromal Cell Cultures Exhibit Heightened Androgen‐Responsiveness

The Prostate, EarlyView.
ABSTRACT Background Benign prostatic hyperplasia (BPH) is the most common disease in aging males. BPH growth is androgen‐dependent, and it appears that androgens preferentially stimulate the growth of BPH as compared to normal prostate. The mechanism of preferential androgen stimulation of BPH growth is not clear.
Wei Chen, Fulu Dong, Mohammad Reza Askarpour, Laura E. Pascal, Rajiv Dhir, Uma Chandran, Bruce L. Jacobs, Donald B. DeFranco, Naoki Yoshimura, Zhou Wang   +9 more
wiley   +1 more source

Intracardiac Metastasis From a Testicular Yolk Sac Tumor With Brain and Pulmonary Involvement: A Multimodality Management Case Report. [PDF]

Clin Case Rep
ABSTRACT Cardiac metastasis from non‐seminomatous germ cell tumors (NSGCTs) is exceedingly rare and represents an aggressive disease course. We report a 37‐year‐old man with a testicular yolk sac tumor who initially declined adjuvant therapy after orchiectomy.
Fazilat-Panah D, Masudian M, Heidarian M.   +2 more
europepmc   +2 more sources

Testicular Adrenal Rest Tumor [PDF]

, 2018
Purpose: Testicular Adrenal Rest Tumor (TART) is a condition that is seen in men with congenital adrenal hyperplasia and particularly in uncontrolled cases.
Mehmet GÜVEN, Balsak, Belma Özlem Tural, Alpaslan Kemal TUZCU, Pekkolay, Zafer, Tuzcu, Alpaslan Kemal, Güven, Mehmet, Belma Özlem TURAL BALSAK, Zafer PEKKOLAY   +7 more
core   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source

A 24‐year‐old patient with testicular benign capillary hemangioma: A rare case report

Clinical Case Reports
Key Clinical Message The importance of urologists and pathologists being knowledgable about primary testicular hemangiomas and other benign adult testicular neoplasms, though rare, is crucial.
Hasan Haydar, Mouhammed Sleiay, Sliman Marina, Abdulrahman Haydar, Mohammed Alqreea, Bauthaina Alomar, Mohamad Yasin Lutfi, Simon Youssef   +7 more
doaj   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Metastatic primary testicular carcinoid tumor managed with radical orchiectomy, retroperitoneal lymph node dissection and inferior vena cava excision: Case report

Urology Case Reports, 2017
Metastatic primary testicular carcinoid tumor remains a very rare condition. We report the first case of metastatic primary testicular carcinoid tumor where along retroperitoneal lymph node dissection excision of the Inferior Vena Cava was also performed.
H.K. Bangash, D. Hayne, I.A. Thyer
doaj   +1 more source