Results 161 to 170 of about 4,735,472 (312)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

T cell-nanodrug conjugates synchronize vascular normalization and immune activation for solid tumor therapy. [PDF]

Sci Adv
Yang X, Su Y, Ye X, Liu C, Zhao X, Su Y, Dong Q, Zeng W, Sui X, Zhou X, Chen G, Zhang Y, Wu D, Liu J.   +13 more
europepmc   +1 more source

Gene transfer in tumor therapy

Annals of Oncology, 1994
FORNI G., PARMIANI G., GUARINI, Anna, FOA, Roberto   +3 more
openaire   +3 more sources

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Trans‐omic analyses identified novel prognostic biomarkers for colorectal cancer survival

Clinical and Translational Medicine, 2023
Chanjuan Liu, Furong Yan, Dongli Song, Yiming Zeng, Tiankui Qiao, Duojiao Wu, Yunfeng Cheng, Hao Chen   +7 more
doaj   +1 more source

Harnessing Silicene-to-Silicic Acid Conversion for Organelle-Specific Silica Deposition in Tumor Therapy. [PDF]

Adv Mater
Shang T, You C, Zhao J, Wang A, Shen J, Zhu Y, Yang J, Xiao K, Sun W, Ma Y, Zhu W, Lei Q.   +11 more
europepmc   +1 more source

Photothermal therapy of melanoma tumor using multiwalled carbon nanotubes

, 2017
Zahra Sobhani,1,2 Mohammad Ali Behnam,3 Farzin Emami,3 Amirreza Dehghanian,4 Iman Jamhiri5 1Quality Control Department, Faculty of Pharmacy, 2Center for Nanotechnology in Drug Delivery, Faculty of Pharmacy, Shiraz University of Medical Sciences, 3Opto ...
Jamhiri I, Sobhani Z, Emami F, Dehghanian A, Behnam MA   +4 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Bibliometric analysis of genetically engineered bacteria in tumor therapy. [PDF]

Front Microbiol
Zhu Y, Yin Y, Li Y, Wang Q, Chen Y, Gu K, Yang R, Zhou M, Chen D.   +8 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source