Results 231 to 240 of about 4,735,472 (312)

Large vesicles from ageing neutrophils: novel safeguards for the resolution of inflammation

Signal Transduction and Targeted Therapy
Christopher Dietz-Fricke, Florian R. Greten   +1 more
doaj   +1 more source

Correction: Carrier-free supramolecular nanoassemblies of pure LSD1 inhibitor for effective anti-tumor therapy. [PDF]

Front Chem
Li B, Zhang X, Li J.
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Cancer-Associated Fibroblast-Targeted Nanomedicine in Solid Tumor Therapy: From Mechanisms of Therapeutic Resistance to Precision Stromal Modulation. [PDF]

Int J Nanomedicine
Wang R, Zhang Z, Du J, Chen J, Teng Y, Wang Q, Wu Z, Yang T, Jiang H.   +8 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Gut microbial carcinogen metabolism: another avenue to cancer

Signal Transduction and Targeted Therapy
Florian R. Greten, Melek C. Arkan
doaj   +1 more source

Chitosan-based nanotheranostics integrated dual-modal imaging and combinatorial tumor therapy for EGFR-TKI resistance reversal. [PDF]

Mater Today Bio
Zheng F, Su Y, Sun X, Tan D, Wang Y, Li X, Gao Y.   +6 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Morpho-crystallo-electronic Co-optimization of PtAu/GOx nanozyme for enhanced NIR-II photothermal-cascade catalytic tumor therapy. [PDF]

Mater Today Bio
Sun X, Zhang L, Niu J, Sun G, Ling H, Wang S, Zhang R, Chen S, Deng H, Kong X, Zhuo X, Zhang H.   +11 more
europepmc   +1 more source

Oncofetal cell states: cell plasticity drives invasion in premetastatic colorectal tumors

Signal Transduction and Targeted Therapy
Mahmoud N. A. Amer, Florian R. Greten
doaj   +1 more source