Results 71 to 80 of about 2,874,529 (208)
Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded
MedComm, Volume 6, Issue 7, July 2025.Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin +8 more
wiley +1 more source
Tumoral Calcinosis in England [PDF]
BMJ, 1973 Two cases of tumoral calcinosis are presented in patients living in England. The clinical and pathological features are described and attention is drawn to the need to consider exotic diseases in patients who have originated from or lived in the tropics.The cause of tumoral calcinosis is not known. It may be a metabolic disease of obscure aetiology but
L. Klenerman +3 more
openaire +3 more sources
Intractable & Rare Diseases Research, 2021 Hyperphosphatemic familial tumoral calcinosis (HFTC) is an extremely rare autosomal recessive disorder caused by variants in the GALNT3 (N-acetylgalactosaminyltransferase 3), FGF23 (Fibroblast Growth Factor-23) and αKL (α-Klotho) genes, which results in ...
D. Dayal +5 more
semanticscholar +1 more source
Osteoclastogenesis in Patients With Systemic Sclerosis With and Without Calcinosis Cutis
ACR Open Rheumatology, Volume 7, Issue 4, April 2025.Objective We aimed to assess whether the presence of radiographically confirmed calcinosis of the hands in patients with systemic sclerosis (SSc) is associated with increased osteoclastogenesis. Methods We recruited 20 patients with SSc (10 with calcinosis and 10 without calcinosis) and 10 age‐ and gender‐matched healthy controls. Hand radiographs were
Antonia Valenzuela +6 more
wiley +1 more source
Cerebrovascular Involvement in Systemic Sclerosis
ACR Open Rheumatology, Volume 7, Issue 4, April 2025.Systemic sclerosis (SSc) is a chronic autoimmune rheumatic disease characterized by vascular damage, immune system dysregulation and fibrosis. The hallmark features include microvascular alterations and progressive tissue fibrosis, affecting skin, internal organs as well central and peripheral nervous system, adding to the disease's complexity and ...
Maurizio Cutolo +4 more
wiley +1 more source
Idiopathic Tumoral Calcinosis – Rare Clinico Pathological Entity: A Report of Two Cases [PDF]
Journal of Clinical and Diagnostic Research, 2017 Tumoral calcinosis is a rare disease reported mainly in blacks of tropical and subtropical African regions. It is characterized by tumour-like periarticular deposits of calcium that are found in the regions of the hip, shoulder, elbow and small joints ...
Sreedevi Jakka +4 more
doaj +1 more source
The emerging role of neutrophil extracellular traps in autoimmune and autoinflammatory diseases
MedComm, Volume 6, Issue 3, March 2025.Neutrophil extracellular traps (NETs) released by neutrophils in response to pathogens exhibit dual anti‐inflammatory and proinflammatory effects. While effective in pathogen capture and inflammation resolution, imbalanced NET formation can lead to tissue damage and exacerbate inflammatory responses in autoimmune diseases.
Liuting Zeng +4 more
wiley +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
David Ranzinger +4 more
wiley +1 more source
Clinical Case Reports, Volume 13, Issue 2, February 2025.ABSTRACT This report highlights a severe manifestation of chronic kidney disease‐mineral and bone disorder (CKD‐MBD) in a hemodialysis patient: periarticular calcifications causing recurrent inflammation mimicking infection. Diagnostics excluded infections and autoimmune disorders, identifying CKD‐MBD as the cause.
Janis Timsans +3 more
wiley +1 more source
The Complexities and Challenges of Managing Genetic Causes of Hyperphosphataemia, a Case Report
Journal of Paediatrics and Child Health, EarlyView.
Farrah Rodrigues +3 more
wiley +1 more source