Results 111 to 120 of about 39,735 (143)
Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor
Cancer Communications, EarlyView.Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai +6 more
wiley +1 more source
Cancer Communications, EarlyView.Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu +12 more
wiley +1 more source
Chemistry &Biodiversity, EarlyView.ABSTRACT The chemical study of the ethanolic extract from the roots of Vicia faba led to the isolation of two isoflavonoids, alfalone and 8‐O‐methylretusine, as well as a mixture of rotenoids, including clitoriacetal and clitoriacetal B, the latter of which is reported for the first time.
Victor Menezes Sipoloni +8 more
wiley +1 more source
ChemistryEurope, EarlyView.Modification of the ferrociphenol structure by a phosphine moiety appended to the originally unsubstituted cyclopentadienyl ring of the ferrocene unit represents a new and useful modification of this potent anticancer agent and opens a way to the preparation of new biologically active derivatives (e.g., phosphonium salts) and, mainly, heterobimetallic ...
Magda Křelinová +5 more
wiley +1 more source
Chemistry – A European Journal, Accepted Article.Novel water‐soluble, phosphorescent ruthenium(II) polypyridyl‐glycoconjugates of general formula [Ru{N‐(1,10‐phenanthroline)}2{N‐(1,10‐phenanthrolin‐5‐yl)‐β‐glycopyranosylamine}][Cl]2 (glycopyranosyl = D‐glucopyranosyl (1), D‐mannopyranosyl (2), L‐rhamnopyranosyl (3), L‐xylopyranosyl (4) and 2,3,4‐tri‐O‐acetyl‐L‐xylopyranosyl (5)) and corresponding ...
Elena de la Torre-Rubio +5 more
wiley +1 more source
Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells
Cancer Communications, EarlyView.
Ashley V. Makela +7 more
wiley +1 more source
Harnessing Viral Proteases for Cellular and Molecular Engineering
Chemistry–Methods, EarlyView.Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui +2 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito +9 more
wiley +1 more source