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Tunneling Nanotubes: A Versatile Target for Cancer Therapy
Current Cancer Drug Targets, 2018Currently Cancer is the leading cause of death worldwide. Malignancy or cancer is a class of diseases characterized by uncontrolled cell growth that eventually invade other tissues and develop secondary malignant growth at other sites by metastasis.
Pragyaparamita, Sahu +2 more
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Prions hijack tunnelling nanotubes for intercellular spread
Nature Cell Biology, 2009In variant Creutzfeldt-Jakob disease, prions (PrP(Sc)) enter the body with contaminated foodstuffs and can spread from the intestinal entry site to the central nervous system (CNS) by intercellular transfer from the lymphoid system to the peripheral nervous system (PNS). Although several means and different cell types have been proposed to have a role,
Gousset, Karine +12 more
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Intercellular Tunneling Nanotubes as Natural Biophotonic Conveyors
ACS NanoTunneling nanotubes (TNTs), submicrometer membranous channels that bridge and connect distant cells, play a pivotal role in intercellular communication. Organelle transfer within TNTs is crucial in regulating cell growth, signal transmission, and disease progression.
Zhiyong Gong +6 more
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Terminating Structures of Tunneling Nanotubes
2023Amer Soc Cell Biol,European Mol Biol ...
Ayres, V. +3 more
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The Ways of Actin: Why Tunneling Nanotubes Are Unique Cell Protrusions
Trends in Cell Biology, 2021J Michael Henderson, Chiara Zurzolo
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Tunneling Nanotubes: The Fuel of Tumor Progression?
Trends in Cancer, 2020Christel Brou, Chiara Zurzolo
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A Role for Tunneling Nanotubes in Autophagy
Autophagie ist ein Clearance-Mechanismus, durch den zytoplasmisches Material stochastisch in einem Doppelmembranvesikel, dem sogenannten Autophagosom, eingeschlossen und bei der Fusion mit Lysosomen abgebaut wird. Vier entscheidende Akteure bei der Bildung von Autophagosomen sind die WIPI-Proteine, von WIPI1 bis WIPI4, die an der Initiierung ...openaire +2 more sources

