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Tunneling Nanotubes: Implications for Chemoresistance
Tunneling nanotubes (TNTs) are thin, membranous protrusions that connect cells and allow for the transfer of various molecules, including proteins, organelles, and genetic material. TNTs have been implicated in a wide range of biological processes, including intercellular communication, drug resistance, and viral transmission. In cancer, they have beenSanyukta, Padmanabhan +3 more
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Tunneling nanotube formation is essential for the regulation of osteoclastogenesis
Journal of Cellular Biochemistry, 2013AbstractOsteoclasts are the multinucleated giant cells formed by cell fusion of mononuclear osteoclast precursors. Despite the finding of several membrane proteins involving DC‐STAMP as regulatory proteins required for fusion among osteoclast precursors, cellular and molecular events concerning this process are still ambiguous.
Akira, Takahashi +8 more
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Nanotube ferroelectric tunnel junctions with an ultrahigh tunneling electroresistance ratio
Materials HorizonsLow-dimensional ferroelectric tunnel junctions are appealing for the realization of nanoscale nonvolatile memory devices due to their inherent advantages of device miniaturization.
Jiu-Long Wang +6 more
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Tunneling Nanotubes: A Versatile Target for Cancer Therapy
Current Cancer Drug Targets, 2018Currently Cancer is the leading cause of death worldwide. Malignancy or cancer is a class of diseases characterized by uncontrolled cell growth that eventually invade other tissues and develop secondary malignant growth at other sites by metastasis.
Pragyaparamita, Sahu +2 more
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Prions hijack tunnelling nanotubes for intercellular spread
Nature Cell Biology, 2009In variant Creutzfeldt-Jakob disease, prions (PrP(Sc)) enter the body with contaminated foodstuffs and can spread from the intestinal entry site to the central nervous system (CNS) by intercellular transfer from the lymphoid system to the peripheral nervous system (PNS). Although several means and different cell types have been proposed to have a role,
Gousset, Karine +12 more
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Intercellular Tunneling Nanotubes as Natural Biophotonic Conveyors
ACS NanoTunneling nanotubes (TNTs), submicrometer membranous channels that bridge and connect distant cells, play a pivotal role in intercellular communication. Organelle transfer within TNTs is crucial in regulating cell growth, signal transmission, and disease progression.
Zhiyong Gong +6 more
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Terminating Structures of Tunneling Nanotubes
2023Amer Soc Cell Biol,European Mol Biol ...
Ayres, V. +3 more
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Scanning tunneling microscopy of carbon nanotubes and nanocones
Carbon, 1995Abstract Tubular and conical carbon shell structures can be synthesized in the vapor phase. Very hot carbon vapor, after being deposited onto highly oriented pyrolytic graphite (HOPG), forms a variety of nanostructures, in particular single-shell tubes, multishell tubes, bundles of tubes, and cones.
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The Ways of Actin: Why Tunneling Nanotubes Are Unique Cell Protrusions
Trends in Cell Biology, 2021J Michael Henderson, Chiara Zurzolo
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