Results 61 to 70 of about 59,389 (269)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
International Journal of Maritime Technology, 2015 In this paper, three-dimensional two phase turbulent free surface flow is solved by an in-house code. The incompressible Reynolds average Navier-Stocks equations (RANS) with k-ε turbulence model are solved by the finite volume method in the non ...
Hashem Moradi +2 more
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Cogent EngineeringVarious studies have been conducted to improve the tribological performance of thrust bearings. In the present study, thermohydrodynamic (THD) analysis was carried out to explore the performance of textured thrust bearings with rectangular dimples in ...
Mohammad Tauviqirrahman +6 more
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Comparison Study of Flow in A Compound Channel: Experimental and Numerical Method Using Large Eddy Simulation SDS-2DH Model [PDF]
ITB Journal of Engineering Science, 2007 Flow modeling in a compound channel is a complex matter. Indeed, due to the smaller velocities in the floodplains than in the main channel, shear layers develop at the interfaces between two stage channels, and the channel conveyance is affected by a ...
Eka Oktariyanto Nugroho, Syunsuke Ikeda
doaj
Propulsion and Power Research, 2020 This experiment used a parallel array of hot wire probes to simultaneously measure the temperature and velocity fields in the non-isothermal turbulent boundary layer of a rotating straight channel. The Reynolds numbers are 15,000 and 25,000, respectively.
Ran Gao +4 more
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SPIE Proceedings, 2012 We recently developed a new approach to get a stabilized image from a sequence of frames acquired through atmospheric turbulence. The goal of this algorihtm is to remove the geometric distortions due by the atmosphere movements. This method is based on a variational formulation and is efficiently solved by the use of Bregman iterations and the operator
Yu Mao, Jérôme Gilles
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source