Results 31 to 40 of about 455,438 (280)

Predicting Drag-Reducing Wall Turbulence of Surfactant Solution by Direct Numerical Simulation

Journal of Fluid Science and Technology, 2012
We performed direct numerical simulations (DNS) of turbulent channel flow of surfactant solution to investigate characteristics of modulated wall turbulence and turbulent drag reduction.
Takashi OHTA, Yuto USUI, Hiroshi YASOSHIMA   +2 more
doaj   +1 more source

Synthesis of patient-specific multipoint 4D flow MRI data of turbulent aortic flow downstream of stenotic valves

Scientific Reports, 2022
We propose to synthesize patient-specific 4D flow MRI datasets of turbulent flow paired with ground truth flow data to support training of inference methods.
Pietro Dirix, Stefano Buoso, Eva S. Peper, Sebastian Kozerke   +3 more
doaj   +1 more source

Changes in turbulent dissipation in a channel flow with oscillating walls

, 2012
Harmonic oscillations of the walls of a turbulent plane channel flow are studied by direct numerical simulations to improve our understanding of the physical mechanism for skin-friction drag reduction. The simulations are carried out at constant pressure
Batchelor, Claudio Ottonelli, Davidson, Garabedian, Hinze, Maurizio Quadrio, Pierre Ricco, Tennekes, Yosuke Hasegawa   +8 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Large-Eddy simulation of pulsatile blood flow [PDF]

, 2009
Large-Eddy simulation (LES) is performed to study pulsatile blood flow through a 3D model of arterial stenosis. The model is chosen as a simple channel with a biological type stenosis formed on the top wall.
Despande, Fry, Frydrychowicz, Fung, Ghalichi, Giles Roditi, Jones, Lee, Liang, Lieber, Malek, Manosh C. Paul, Md. Mamun Molla, Mittal, Mittal, Pedley, Pedley, Piomelli, Scotti, Smagorinsky, Stonebridge, Sutera, Younis   +22 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The rise of fully turbulent flow

, 2015
Over a century of research into the origin of turbulence in wallbounded shear flows has resulted in a puzzling picture in which turbulence appears in a variety of different states competing with laminar background flow.
A Cros, A Lundbladh, AP Willis, B Eckhardt, B Hof, Baofang Song, Björn Hof, D Barkley, D Barkley, D Barkley, D Coles, D Coles, D Moxey, D Samanta, Dwight Barkley, G Kawahara, G Lemoult, Grégoire Lemoult, H Schlichting, HW Emmons, I Wygnanski, IJ Wygnanski, J Gibson, J Rinzel, J Tyson, K Avila, KR Sreenivasan, M Avila, M Avila, M Chantry, M Holzner, M Nishi, M Sipos, Marc Avila, N Tillmark, O Reynolds, RR Kerswell, SB Pope, T Mullin, Vasudevan Mukund, Y Duguet   +40 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Large-Scale Flow Structure in Turbulent Poiseuille Flows at Low-Reynolds Numbers

Journal of Fluid Science and Technology, 2012
Direct numerical simulations of a spectral method are performed to study the turbulent channel flow at the low-Reynolds numbers, where the quasi-laminar and turbulent regions simultaneously appear and form the stripe pattern, which is floated downstream ...
Koji FUKUDOME, Oaki IIDA
doaj   +1 more source