Results 81 to 90 of about 3,253,485 (285)

Turbulent Events and Gas-Side Mass Transfer Coefficients in a Wavy Air-Water Stratified Flow [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2011
Turbulence structure on the gas side of a wavy stratified flow was experimentally investigated in a near horizontal 18.7 cm (H) 10 cm (W) 5.5m (L) rectangular duct.By applying the Variable Interval Time Averaging (VITA) technique to the hot wire ...
Mohsen Nasr Esfahany, Nazi Amanatchi
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Turbulence Models Application in Air Flow of Crossflow Turbine

open access: yesInternational Journal of Technology, 2018
Using the CFD method as the initial analysis for experiments has more benefits, including saving time and costs. The variable of flow parameters and geometry can be easily developed to get the desired results.
Gun Gun R. Gunadi   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Acceleration in turbulent channel flow

open access: yes, 2010
We use Direct Numerical Simulations of turbulent channel flow to study the acceleration A corresponding to the full fluid velocity u and the acceleration a corresponding to the fluctuating velocity u? ? u?hui where hui is the mean flow.
S. W. Coleman   +7 more
core   +1 more source

On the generation of drift flows in wall-bounded flows transiting to turbulence

open access: yesTheoretical and Applied Mechanics Letters, 2018
: Despite recent progress, laminar-turbulent coexistence in transitional planar wall-bounded shear flows is still not well understood. Contrasting with the processes by which chaotic flow inside turbulent patches is sustained at the local (minimal flow ...
Paul Manneville
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

On the non-local turbulent transport and non-gradient thermal diffusion phenomena in HVAC systems [PDF]

open access: yesFME Transactions, 2012
The turbulence structure investigation is essential for understanding the physics of flow-thermodynamic processes in Heating, Ventilation and Air conditioning (HVAC) systems.
Burazer Jela M.   +2 more
doaj  

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