Results 91 to 100 of about 3,253,485 (285)

Simulation of Vertical Plane Turbulent Jet in Shallow Water

open access: yesAdvances in Civil Engineering, 2011
A plane, turbulent, nonbuoyant, vertical jet in shallow water is simulated numerically using a three-dimensional computation model employing standard 𝑘-𝜀 and renormalized group 𝑘-𝜀 turbulent closure schemes.
T. N. Aziz, A. A. Khan
doaj   +1 more source

SIMULATION OF TURBULENCE AS A «VORTEX BACKFILL»

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2018
The new method of simulation and the turbulent flow research, based on representation about turbulence as a current through «vortex backfill» is offered. The method of local fluctuations offered earlier is applied to its realization.
L. E. Melamed, G. A. Filippov
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Numerical Simulation on Temperature Field of Hot Rolled Q215 Steel Bar Cooling by Turbulent Flow Process

open access: yesTeshugang, 2007
Tempered martensite can be formed at surface of bar to increase its mechanical properties by higher efficient tube type turbulent flow cooling system after hot rolling of bar products.
晋艳娟   +4 more
doaj  

Age-Related Vascular Changes Affect Turbulence in Aortic Blood Flow

open access: yesFrontiers in Physiology, 2018
Turbulent blood flow is implicated in the pathogenesis of several aortic diseases but the extent and degree of turbulent blood flow in the normal aorta is unknown.
Hojin Ha   +18 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Characteristics of turbulence in free convection flow past a vertical plate. [PDF]

open access: yes, 1972
PhDAn experimental and theoretical investigation of the turbulent free convection boundary layer on a vertical plane surface in air has been conducted.
Smith, Ronald Robin
core   +3 more sources

An Approach to Calculate Leakage Flow, Stiffness and Damping of Annular Seals in Turbulent Flow Using Lubrication Theory, Part I: Analysis

open access: yesTribology Online, 2007
This paper presents a general theoretical approach to evaluate the leakage flow, stiffness and damping of annular seals in turbulent flow regime including fluid inertia using turbulent lubrication theory.
Satyam Shivam Gautam, Mihir Kumar Ghosh
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

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