Results 91 to 100 of about 292,116 (302)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Transition of a vortex ring measured by 3D scanning Tomo-PIV [PDF]

open access: yes, 2016
A vortex ring with piston-based Reynolds number Rep=4650 is studied experimentally by means of time-resolved scanning tomographic PIV. The present measurement technique provides the so-called 4D flow field, thus enables revealing the vortex ring’s ...
Bruecker, C., Pointz, B., Sun, Z.
core  

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Recurrent bursts via linear processes in turbulent environments

open access: yes, 2014
Large-scale instabilities occurring in the presence of small-scale turbulent fluctuations are frequently observed in geophysical or astrophysical contexts but are difficult to reproduce in the laboratory.
Brethouwer, Geert   +4 more
core   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

A study of the local pressure field in turbulent shear flow and its relation to aerodynamic noise generation Semiannual status report, 1 Aug. 1970 - 31 Jan. 1971 [PDF]

open access: yes
Relation of Eulerian and Lagrangian structure of pseudosound pressure and velocity fields in turbulent shear flow to aerodynamic noise ...
Jones, B. G., Spencer, B. W.
core   +1 more source

Lagrangian dynamics and statistical geometric structure of turbulence

open access: yes, 2006
The local statistical and geometric structure of three-dimensional turbulent flow can be described by properties of the velocity gradient tensor. A stochastic model is developed for the Lagrangian time evolution of this tensor, in which the exact ...
A. Tsinober   +9 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Experimental investigation of peripheral-wall injection techniques in a water vortex tube [PDF]

open access: yes
Effect of peripheral wall injection technique used to drive water vortex tube on structure and thickness of turbulent mixing region and on flow patterns in boundary ...
Travers, A.
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

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