Results 81 to 90 of about 292,116 (302)
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Metals, 2018 Large eddy simulation (LES) of transient magnetohydrodynamic (MHD) turbulent flow under a single-ruler electromagnetic brake (EMBr) in a laboratory-scale, continuous-casting mold is presented.
Zhongqiu Liu +6 more
doaj +1 more source
Discrete-vortex simulation of pulsating flow on a turbulent leading-edge separation bubble [PDF]
Studies are made of the turbulent separation bubble in a two-dimensional semi-infinite blunt plate aligned to a uniform free stream with a pulsating component. The discrete-vortex method is applied to simulate this flow situation because this approach is
Kiya, Masaru +2 more
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Coherent structures in localised and global pipe turbulence
, 2008 The recent discovery of unstable travelling waves (TWs) in pipe flow has been hailed as a significant breakthrough with the hope that they populate the turbulent attractor.
Kerswell, R. R., Willis, A. P.
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Turbulence structures in non-uniform flows
Advances in Water Resources, 2008 This study investigates turbulence structures in steady and non-uniform flows. Equations of Reynolds shear stress and turbulent velocity fluctuations are derived and their physical interpretations are explained. The theoretical results show that, different from previous studies, the variation of water surface can generate the wall-normal velocity ...
Yang, Shuqing, Chow, A. T.
openaire +3 more sources
Experimental and theoretical study of combustion jet ignition [PDF]
A combustion jet ignition system was developed to generate turbulent jets of combustion products containing free radicals and to discharge them as ignition sources into a combustible medium.
Chen, D. Y. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Twisted Contact Structures in Turbulent Flows
INCAS BULLETIN, 2019 The “hairpin” vortical structure initiated from a conceptual model of Theodorsen refers to a Ω-shaped vortex with two streamwise-oriented legs connected via a raised spanwise-oriented arch. Both computational and experimental studies in flow visualization revealed considerable disagreement as to the underlying hairpin vortex generation mechanism as ...
Horia DUMITRESCU +2 more
openaire +2 more sources