Results 61 to 70 of about 292,116 (302)

Constructal law of vascular trees for facilitation of flow. [PDF]

open access: yesPLoS ONE, 2014
Diverse tree structures such as blood vessels, branches of a tree and river basins exist in nature. The constructal law states that the evolution of flow structures in nature has a tendency to facilitate flow.
Mohammad S Razavi   +3 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

The Structure of Turbulent Shear Flow [PDF]

open access: yesNature, 1957
The Structure of Turbulent Shear Flow By Dr. A. A. Townsend. Pp. xii + 315. 8¾ in. × 5½ in. (Cambridge: At the University Press.) 40s.
  +5 more sources

Stem stiffness functionality in a submerged canopy patch under oscillatory flow

open access: yesScientific Reports, 2023
Seagrass canopies are coastal ecosystems that are able to modify the abiotic environment through their architectural structure. They have different structural parameters, such as plant stem stiffness, patch length and canopy density, all of which ...
Aina Barcelona   +2 more
doaj   +1 more source

Data on the influence of dynamical impact by mixing on characteristics of turbulent flows in circular pipes

open access: yesData in Brief, 2022
The article presents experimental data on the kinematic structure of flows in circular channels in conditions of dynamical impact on the flow. The experimental data on the influence of dynamical impact by mixing on flow parameters were obtained. Averaged
Andrei Miheev
doaj   +1 more source

Master-modes in 3D turbulent channel flow [PDF]

open access: yes, 2008
Turbulent flow fields can be expanded into a series in a set of basic functions. The terms of such series are often called modes. A master- (or determining) mode set is a subset of these modes, the time history of which uniquely determines the time ...
Bondarenko, Maksym, Chernyshenko, Sergei
core   +1 more source

A doubly-localized equilibrium solution of plane Couette flow

open access: yes, 2014
We present an equilibrium solution of plane Couette flow that is exponentially localized in both the spanwise and streamwise directions. The solution is similar in size and structure to previously computed turbulent spots and localized, chaotically ...
Brand, Evan, Gibson, John F.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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