Results 31 to 40 of about 7,714 (269)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Electromagnetic enhancement of turbulent heat transfer
We performed large eddy simulations (LES) of the turbulent natural convection of an electrically conductive fluid (water with 7% Na2SO4 electrolyte solution) in a moderate (4:4:1) aspect ratio enclosure heated from below and cooled from above and subjected to external nonuniformly distributed electromagnetic fields.
openaire +4 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
DNS Study of Effects of Suddenly-Vanishing Wall Heating in Turbulent Boundary Layer
The objective of this study is to investigate a thermal field in the turbulent boundary layer by means of direct numerical simulation (DNS), in which the wall heating has suddenly vanished in the downstream region, i.e., the wall is heated by a constant ...
Hirofumi HATTORI +2 more
doaj +1 more source
Bubbly turbulence with heat transfer [PDF]
Bubble injection in convective flows has proven to be a useful method of enhancing heat transfer. In order to understand the underlying physics behind bubble induced heat transfer enhancement, in this thesis we study the global and local flow statistics in a canonical vertical natural convection flow with bubble injection.
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Numerical Analysis of Turbulent Mixed Convection in Vertical Annular Channel
Reactor cavity cooling system (RCCS) is a competitive residual heat removal scheme for small modular reactors. In this paper, the RCCS has been simplified to a scenario that ascending air flow is got heated in vertical annular channels and driven by ...
HU Xiangjie;WEN Jiming;GAO Puzhen;TIAN Ruifeng
doaj
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
High Reynold Number LES of a Rotating Two-Pass Ribbed Duct
Cooling of gas turbine blades is critical to long term durability. Accurate prediction of blade metal temperature is a key component in the design of the cooling system.
Danesh Tafti, Cody Dowd, Xiaoming Tan
doaj +1 more source
Turbulence and heat transfer are two critical factors in the chain of world energy consumption. Hence, development of more efficient energy transfer techniques in engineering applications through control and optimization of the thermal turbulent boundary
Shima Soleimani, Steven Eckels
doaj +1 more source

